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- Cofactor_(biochemistry) abstract "A cofactor is a non-protein chemical compound that is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations.Cofactors can be classified depending on how tightly they bind to an enzyme, with loosely bound cofactors termed coenzymes and tightly bound cofactors termed prosthetic groups. Some sources also limit the use of the term "cofactor" to inorganic substances. An inactive enzyme without the cofactor is called an apoenzyme, while the complete enzyme with cofactor is called a holoenzyme.Some enzymes or enzyme complexes require several cofactors. For example, the multienzyme complex pyruvate dehydrogenase at the junction of glycolysis and the citric acid cycle requires five organic cofactors and one metal ion: loosely bound thiamine pyrophosphate (TPP), covalently bound lipoamide and flavin adenine dinucleotide (FAD), and the cosubstrates nicotinamide adenine dinucleotide (NAD+) and coenzyme A (CoA), and a metal ion (Mg2+).Organic cofactors are often vitamins or are made from vitamins. Many contain the nucleotide adenosine monophosphate (AMP) as part of their structures, such as ATP, coenzyme A, FAD, and NAD+. This common structure may reflect a common evolutionary origin as part of ribozymes in an ancient RNA world. It has been suggested that the AMP part of the molecule can be considered a kind of "handle" by which the enzyme can "grasp" the coenzyme to switch it between different catalytic centers.".
- Cofactor_(biochemistry) thumbnail Succinate_Dehydrogenase_1YQ3_Electron_Carriers_Labeled.png?width=300.
- Cofactor_(biochemistry) wikiPageExternalLink cofactors.ppt.
- Cofactor_(biochemistry) wikiPageExternalLink CoFactor.
- Cofactor_(biochemistry) wikiPageID "543048".
- Cofactor_(biochemistry) wikiPageRevisionID "605829777".
- Cofactor_(biochemistry) hasPhotoCollection Cofactor_(biochemistry).
- Cofactor_(biochemistry) subject Category:Cofactors.
- Cofactor_(biochemistry) subject Category:Enzymes.
- Cofactor_(biochemistry) type Abstraction100002137.
- Cofactor_(biochemistry) type Activator114723079.
- Cofactor_(biochemistry) type Catalyst114723628.
- Cofactor_(biochemistry) type Chemical114806838.
- Cofactor_(biochemistry) type Cofactor114800706.
- Cofactor_(biochemistry) type Cofactors.
- Cofactor_(biochemistry) type Compound114818238.
- Cofactor_(biochemistry) type Enzyme114732946.
- Cofactor_(biochemistry) type Enzymes.
- Cofactor_(biochemistry) type Macromolecule114944888.
- Cofactor_(biochemistry) type Material114580897.
- Cofactor_(biochemistry) type Matter100020827.
- Cofactor_(biochemistry) type Molecule114682133.
- Cofactor_(biochemistry) type OrganicCompound114727670.
- Cofactor_(biochemistry) type Part113809207.
- Cofactor_(biochemistry) type PhysicalEntity100001930.
- Cofactor_(biochemistry) type Protein114728724.
- Cofactor_(biochemistry) type Relation100031921.
- Cofactor_(biochemistry) type Substance100019613.
- Cofactor_(biochemistry) type Thing100002452.
- Cofactor_(biochemistry) type Unit109465459.
- Cofactor_(biochemistry) comment "A cofactor is a non-protein chemical compound that is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations.Cofactors can be classified depending on how tightly they bind to an enzyme, with loosely bound cofactors termed coenzymes and tightly bound cofactors termed prosthetic groups. Some sources also limit the use of the term "cofactor" to inorganic substances.".
- Cofactor_(biochemistry) label "Cofacteur (biochimie)".
- Cofactor_(biochemistry) label "Cofactor (biochemistry)".
- Cofactor_(biochemistry) label "Cofactor".
- Cofactor_(biochemistry) label "Cofaktor (Biochemie)".
- Cofactor_(biochemistry) label "Cofator (bioquímica)".
- Cofactor_(biochemistry) label "Cofattore (biologia)".
- Cofactor_(biochemistry) label "Kofaktory".
- Cofactor_(biochemistry) label "補因子".
- Cofactor_(biochemistry) label "辅因子".
- Cofactor_(biochemistry) sameAs Kofaktor_(biochemie).
- Cofactor_(biochemistry) sameAs Cofaktor_(Biochemie).
- Cofactor_(biochemistry) sameAs Cofactor.
- Cofactor_(biochemistry) sameAs Cofacteur_(biochimie).
- Cofactor_(biochemistry) sameAs Cofattore_(biologia).
- Cofactor_(biochemistry) sameAs 補因子.
- Cofactor_(biochemistry) sameAs 보조_인자.
- Cofactor_(biochemistry) sameAs Kofaktory.
- Cofactor_(biochemistry) sameAs Cofator_(bioquímica).
- Cofactor_(biochemistry) sameAs m.02nch4.
- Cofactor_(biochemistry) sameAs Q407280.
- Cofactor_(biochemistry) sameAs Q407280.
- Cofactor_(biochemistry) sameAs Cofactor_(biochemistry).
- Cofactor_(biochemistry) wasDerivedFrom Cofactor_(biochemistry)?oldid=605829777.
- Cofactor_(biochemistry) depiction Succinate_Dehydrogenase_1YQ3_Electron_Carriers_Labeled.png.
- Cofactor_(biochemistry) isPrimaryTopicOf Cofactor_(biochemistry).