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- Ghon's_complex abstract "Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. The lesions consist of a calcified focus of infection and an associated lymph node. These lesions are particularly common in children and can retain viable bacteria, so are sources of long-term infection and may be involved in reactivation of the disease in later life.In countries where cow milk infected with Mycobacterium bovis has been eliminated (due to culling of infected cows and pasteurization), primary tuberculosis is usually caused by Mycobacterium tuberculosis and almost always begins in the lungs. Typically, the inhaled bacilli implant in the distal airspaces of the lower part of the upper lobe or the upper part of the lower lobe, usually close to the pleura. As sensitization develops, a 1- to 1.5-cm area of gray-white inflammation with consolidation emerges, known as the Ghon focus. In most cases, the center of this focus undergoes caseous necrosis. Tubercle bacilli, either free or within phagocytes, drain to the regional nodes, which also often caseate. This combination of parenchymal lung lesion and nodal involvement is referred to as the Ghon complex. During the first few weeks there is also lymphatic and hematogenous dissemination to other parts of the body. In approximately 95% of cases, development of cell-mediated immunity controls the infection. Hence, the Ghon complex undergoes progressive fibrosis, often followed by radiologically detectable calcification (Ranke complex), and despite seeding of other organs, no lesions develop. Although they are often confused, Ranke complex and Ghon complex are not synonymous. The Ranke complex is an evolution of the Ghon complex (resulting from further healing and calcification of the lesion).".
- Ghon's_complex wikiPageID "4280679".
- Ghon's_complex wikiPageRevisionID "605679407".
- Ghon's_complex hasPhotoCollection Ghon's_complex.
- Ghon's_complex subject Category:Gross_pathology.
- Ghon's_complex subject Category:Lung_disorders.
- Ghon's_complex subject Category:Tuberculosis.
- Ghon's_complex type Abstraction100002137.
- Ghon's_complex type Attribute100024264.
- Ghon's_complex type Condition113920835.
- Ghon's_complex type Disorder114052403.
- Ghon's_complex type LungDisorders.
- Ghon's_complex type PhysicalCondition114034177.
- Ghon's_complex type State100024720.
- Ghon's_complex comment "Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. The lesions consist of a calcified focus of infection and an associated lymph node.".
- Ghon's_complex label "Complejo de Ghon".
- Ghon's_complex label "Complexo de Ghon".
- Ghon's_complex label "Ghon's complex".
- Ghon's_complex label "Первичный туберкулёзный комплекс".
- Ghon's_complex sameAs Complejo_de_Ghon.
- Ghon's_complex sameAs Complexo_de_Ghon.
- Ghon's_complex sameAs m.0btxv8.
- Ghon's_complex sameAs Q2086658.
- Ghon's_complex sameAs Q2086658.
- Ghon's_complex sameAs Ghon's_complex.
- Ghon's_complex wasDerivedFrom Ghon's_complex?oldid=605679407.
- Ghon's_complex isPrimaryTopicOf Ghon's_complex.