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- TRPA_(channel) abstract "TRPA is a family of transient receptor potential ion channels.The sole member of the TRPA sub-family, TRPA1, contains 14 N-terminal ankyrin repeats and is believed to function as a mechanical stress sensor. It is expressed in the dorsal root ganglion, trigeminal ganglion, and hair cells. The temperature sensitivity of TRPA1 is highly disputed, with some reports claiming that it is activated by noxiously cold stimuli and others disputing such a claim[citation needed]. TRPA1 is known to be activated by compounds capable of forming covalent chemical bonds with the protein's cysteins like isothiocyanates, which are the pungent chemicals in substances such as mustard oil and wasabi and Michael acceptors such as cinnamaldehyde in cinnamon, amongst numerous other substances. Non-covalent activators of TRPA1 also exists, such as methyl salicylate in winter green oil and the synthetic compound PF-4840154.".
- TRPA_(channel) arm "q".
- TRPA_(channel) band "13".
- TRPA_(channel) chromosome "8".
- TRPA_(channel) entrezgene "8989".
- TRPA_(channel) hgncid "497".
- TRPA_(channel) omim "604775".
- TRPA_(channel) refseq "NM_007332".
- TRPA_(channel) symbol "ANKTM1".
- TRPA_(channel) symbol "TRPA1".
- TRPA_(channel) uniprot "O75762".
- TRPA_(channel) wikiPageExternalLink www.trpchannel.org.
- TRPA_(channel) wikiPageID "11896859".
- TRPA_(channel) wikiPageRevisionID "593219308".
- TRPA_(channel) altsymbols "ANKTM1".
- TRPA_(channel) arm "q".
- TRPA_(channel) band "13".
- TRPA_(channel) chromosome "8".
- TRPA_(channel) entrezgene "8989".
- TRPA_(channel) hasPhotoCollection TRPA_(channel).
- TRPA_(channel) hgncid "497".
- TRPA_(channel) iupharId "yes".
- TRPA_(channel) name Transient_receptor_potential_cation_channel,_member_A1.
- TRPA_(channel) omim "604775".
- TRPA_(channel) refseq "NM_007332".
- TRPA_(channel) symbol "TRPA1".
- TRPA_(channel) uniprot "O75762".
- TRPA_(channel) subject Category:Ion_channels.
- TRPA_(channel) subject Category:Membrane_biology.
- TRPA_(channel) type Abstraction100002137.
- TRPA_(channel) type Act100030358.
- TRPA_(channel) type Channel106259898.
- TRPA_(channel) type Communication106252138.
- TRPA_(channel) type Event100029378.
- TRPA_(channel) type IonChannels.
- TRPA_(channel) type PsychologicalFeature100023100.
- TRPA_(channel) type Transmission106251781.
- TRPA_(channel) type YagoPermanentlyLocatedEntity.
- TRPA_(channel) type Biomolecule.
- TRPA_(channel) type Protein.
- TRPA_(channel) type ProteinMolecule.
- TRPA_(channel) type BiologicalObject.
- TRPA_(channel) comment "TRPA is a family of transient receptor potential ion channels.The sole member of the TRPA sub-family, TRPA1, contains 14 N-terminal ankyrin repeats and is believed to function as a mechanical stress sensor. It is expressed in the dorsal root ganglion, trigeminal ganglion, and hair cells. The temperature sensitivity of TRPA1 is highly disputed, with some reports claiming that it is activated by noxiously cold stimuli and others disputing such a claim[citation needed].".
- TRPA_(channel) label "TRPA (channel)".
- TRPA_(channel) sameAs m.02rx6d7.
- TRPA_(channel) sameAs Q7671458.
- TRPA_(channel) sameAs Q7671458.
- TRPA_(channel) sameAs TRPA_(channel).
- TRPA_(channel) wasDerivedFrom TRPA_(channel)?oldid=593219308.
- TRPA_(channel) isPrimaryTopicOf TRPA_(channel).
- TRPA_(channel) name "transient receptor potential cation channel, subfamily A, member 1".