Matches in Ghent University Academic Bibliography for { <https://biblio.ugent.be/publication/01GPB9254PVGVYJN1ES6BJW2V8> ?p ?o. }
Showing items 1 to 37 of
37
with 100 items per page.
- 01GPB9254PVGVYJN1ES6BJW2V8 classification A1.
- 01GPB9254PVGVYJN1ES6BJW2V8 date "2022".
- 01GPB9254PVGVYJN1ES6BJW2V8 language "eng".
- 01GPB9254PVGVYJN1ES6BJW2V8 type journalArticle.
- 01GPB9254PVGVYJN1ES6BJW2V8 hasPart 01GPB9AC5YTJ0E4WCKEKBEXCPQ.pdf.
- 01GPB9254PVGVYJN1ES6BJW2V8 hasPart 01GVD06Z63HMBM2YEM52ANG150.pdf.
- 01GPB9254PVGVYJN1ES6BJW2V8 subject "Biology and Life Sciences".
- 01GPB9254PVGVYJN1ES6BJW2V8 subject "Medicine and Health Sciences".
- 01GPB9254PVGVYJN1ES6BJW2V8 doi "10.1016/j.biomaterials.2022.121830".
- 01GPB9254PVGVYJN1ES6BJW2V8 issn "0142-9612".
- 01GPB9254PVGVYJN1ES6BJW2V8 issn "1878-5905".
- 01GPB9254PVGVYJN1ES6BJW2V8 volume "290".
- 01GPB9254PVGVYJN1ES6BJW2V8 abstract "The brain is protected against invading organisms and other unwanted substances by tightly regulated barriers. However, these central nervous system (CNS) barriers impede the delivery of drugs into the brain via the blood circulation and are therefore considered major hurdles in the treatment of neurological disorders. Consequently, there is a high need for efficient delivery systems that are able to cross these strict barriers. While most research focuses on the blood-brain barrier (BBB), the design of drug delivery platforms that are able to cross the bloodcerebrospinal fluid (CSF) barrier, formed by a single layer of choroid plexus epithelial cells, remains a largely unexplored domain. The discovery that extracellular vesicles (EVs) make up a natural mechanism for information transfer between cells and across cell layers, has stimulated interest in their potential use as drug delivery platform. Here, we report that choroid plexus epithelial cell-derived EVs exhibit the capacity to home to the brain after peripheral administration. Moreover, these vesicles are able to functionally deliver cargo into the brain. Our findings underline the therapeutic potential of choroid plexus-derived EVs as a brain drug delivery vehicle via targeting of the blood-CSF interface.".
- 01GPB9254PVGVYJN1ES6BJW2V8 author 07DB8682-F0EF-11E1-A197-91C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author 11FF74D2-9CBD-11E7-BF46-88FBAD28A064.
- 01GPB9254PVGVYJN1ES6BJW2V8 author 1F1D02F4-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author 30CFFDEE-F0EE-11E1-A9DE-61C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author 7E451A84-C5CA-11E8-8987-A2685607D3EF.
- 01GPB9254PVGVYJN1ES6BJW2V8 author 86984d6b-d85c-11eb-a658-b0ebb3088a23.
- 01GPB9254PVGVYJN1ES6BJW2V8 author F54C4980-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author F589247C-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author F6617AF2-F0ED-11E1-A9DE-61C894A0A6B4.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:33e576d8-5806-4479-9360-2f10bcbc70f7.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:3aa76b10-6101-47a8-93d5-985ce7297df5.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:6129c95f-efd2-43cd-a434-8c16b1247fd1.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:7d84bf8c-46f8-49b6-b291-b9080a20e474.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:88774532-6ffc-48c4-9b53-5a5776b023c1.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:a02c798a-4f64-425a-bfe5-7c00e21b3aee.
- 01GPB9254PVGVYJN1ES6BJW2V8 author urn:uuid:aede2c43-bb2c-4119-934c-c0891ce06b87.
- 01GPB9254PVGVYJN1ES6BJW2V8 dateCreated "2023-01-09T12:46:08Z".
- 01GPB9254PVGVYJN1ES6BJW2V8 dateModified "2024-10-29T19:04:26Z".
- 01GPB9254PVGVYJN1ES6BJW2V8 name "Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics".
- 01GPB9254PVGVYJN1ES6BJW2V8 sameAs LU-01GPB9254PVGVYJN1ES6BJW2V8.
- 01GPB9254PVGVYJN1ES6BJW2V8 sourceOrganization urn:uuid:210a5c92-1a6c-41d1-a303-592be2303b96.
- 01GPB9254PVGVYJN1ES6BJW2V8 sourceOrganization urn:uuid:45ccd30e-e49f-4fac-bf95-3d782fb7eeaa.
- 01GPB9254PVGVYJN1ES6BJW2V8 sourceOrganization urn:uuid:9cc482af-c142-4f53-9713-da3faf3c5a70.
- 01GPB9254PVGVYJN1ES6BJW2V8 type A1.