Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Env_(gene)> ?p ?o. }
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- Env_(gene) abstract "Env is a viral protein that serves to form the viral envelope. The expression of the env gene enables retroviruses to target and attach to specific cell types, and to infiltrate the target cell membrane. Analysis of the structure and sequence of several different env genes suggests that Env proteins are type 1 fusion machines. Type 1 fusion machines initially bind a receptor on the target cell surface, which triggers a conformational change, allowing for binding of the fusion protein. The fusion peptide inserts itself in the host cell membrane and brings the host cell membrane very close to the viral membrane to facilitate membrane fusion. While there are significant differences in sequence of the env gene between retroviruses, the gene is always located downstream of gag, pro, and pol. The env mRNA must be spliced for their expression.The mature product of the env gene is the viral spike protein, which has two main parts: the surface protein (SU) and the transmembrane protein (TM). The tropism of the virus is determined by the SU protein domain because it is responsible for the receptor-binding function of the virus. The SU domain therefore determines the specificity of the virus for a single receptor molecule.".
- Env_(gene) wikiPageID "9876980".
- Env_(gene) wikiPageRevisionID "600117895".
- Env_(gene) chromosome "viral genome".
- Env_(gene) entrezchromosome "NC_001802.1".
- Env_(gene) entrezgene "155971".
- Env_(gene) genlocEnd "8341".
- Env_(gene) genlocStart "5771".
- Env_(gene) hasPhotoCollection Env_(gene).
- Env_(gene) name "env gp160; envelope glycoprotein".
- Env_(gene) organism "HIV 1".
- Env_(gene) refseqprotein "NP_057856.1".
- Env_(gene) symbol "env".
- Env_(gene) taxid "11676".
- Env_(gene) uniprot "P04578".
- Env_(gene) subject Category:Viral_proteins.
- Env_(gene) type Abstraction100002137.
- Env_(gene) type Chemical114806838.
- Env_(gene) type Compound114818238.
- Env_(gene) type Macromolecule114944888.
- Env_(gene) type Material114580897.
- Env_(gene) type Matter100020827.
- Env_(gene) type Molecule114682133.
- Env_(gene) type OrganicCompound114727670.
- Env_(gene) type Part113809207.
- Env_(gene) type PhysicalEntity100001930.
- Env_(gene) type Protein114728724.
- Env_(gene) type Relation100031921.
- Env_(gene) type Substance100019613.
- Env_(gene) type Thing100002452.
- Env_(gene) type Unit109465459.
- Env_(gene) type ViralProteins.
- Env_(gene) comment "Env is a viral protein that serves to form the viral envelope. The expression of the env gene enables retroviruses to target and attach to specific cell types, and to infiltrate the target cell membrane. Analysis of the structure and sequence of several different env genes suggests that Env proteins are type 1 fusion machines. Type 1 fusion machines initially bind a receptor on the target cell surface, which triggers a conformational change, allowing for binding of the fusion protein.".
- Env_(gene) label "Env (gene)".
- Env_(gene) sameAs m.05b6nfr.
- Env_(gene) sameAs Q5380903.
- Env_(gene) sameAs Q5380903.
- Env_(gene) sameAs Env_(gene).
- Env_(gene) wasDerivedFrom Env_(gene)?oldid=600117895.
- Env_(gene) isPrimaryTopicOf Env_(gene).