Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MASP1_(protein)> ?p ?o. }
Showing items 1 to 18 of
18
with 100 items per page.
- MASP1_(protein) abstract "Mannan-binding lectin serine protease 1 also known as mannose-associated serine protease 1 (MASP-1) is an enzyme that in humans is encoded by the MASP1 gene.MASP-1 is involved in the lectin pathway of the complement system and is responsible for cleaving C4 and C2 to form C4b2a, a C3-convertase.MASP-1 is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. MASP-1 is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. MASP-1 is also able to cleave fibrinogen and factor XIII and may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.".
- MASP1_(protein) entrezgene "5648".
- MASP1_(protein) wikiPageID "5989490".
- MASP1_(protein) wikiPageRevisionID "592452056".
- MASP1_(protein) hasPhotoCollection MASP1_(protein).
- MASP1_(protein) subject Category:Complement_system.
- MASP1_(protein) subject Category:EC_3.4.21.
- MASP1_(protein) type Biomolecule.
- MASP1_(protein) type Protein.
- MASP1_(protein) type ProteinMolecule.
- MASP1_(protein) type BiologicalObject.
- MASP1_(protein) comment "Mannan-binding lectin serine protease 1 also known as mannose-associated serine protease 1 (MASP-1) is an enzyme that in humans is encoded by the MASP1 gene.MASP-1 is involved in the lectin pathway of the complement system and is responsible for cleaving C4 and C2 to form C4b2a, a C3-convertase.MASP-1 is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response.".
- MASP1_(protein) label "MASP1 (protein)".
- MASP1_(protein) sameAs m.0fjdvg.
- MASP1_(protein) sameAs Q14905310.
- MASP1_(protein) sameAs Q14905310.
- MASP1_(protein) wasDerivedFrom MASP1_(protein)?oldid=592452056.
- MASP1_(protein) isPrimaryTopicOf MASP1_(protein).