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- Rule_of_three_(statistics) abstract "In statistical analysis, the rule of three states that if a certain event did not occur in a sample with n subjects, 0 to 3/n is a 95% confidence interval for the rate of occurrences in the population. When n is greater than 30, this is a good approximation to results from more sensitive tests.For example, a pain-relief drug is tested on 1500 human subjects, and no adverse event is recorded. From the rule of three, it can be concluded with 95% confidence that fewer than 1 person in 500 (or 3/1500) will experience an adverse event.The rule is useful in the interpretation of clinical trials generally, particularly in phase II and phase III where often there are limitations in duration or statistical power. The rule of three applies well beyond medical research, to any trial done n times. If 300 parachutes are randomly tested and all open successfully, then it is concluded with 95% confidence that fewer than 1 in 100 parachutes with the same characteristics (3/300) will fail.".
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- Rule_of_three_(statistics) hasPhotoCollection Rule_of_three_(statistics).
- Rule_of_three_(statistics) subject Category:Clinical_research.
- Rule_of_three_(statistics) subject Category:Clinical_trials.
- Rule_of_three_(statistics) subject Category:Medical_research.
- Rule_of_three_(statistics) subject Category:Medical_statistics.
- Rule_of_three_(statistics) subject Category:Nursing_research.
- Rule_of_three_(statistics) subject Category:Statistical_approximations.
- Rule_of_three_(statistics) comment "In statistical analysis, the rule of three states that if a certain event did not occur in a sample with n subjects, 0 to 3/n is a 95% confidence interval for the rate of occurrences in the population. When n is greater than 30, this is a good approximation to results from more sensitive tests.For example, a pain-relief drug is tested on 1500 human subjects, and no adverse event is recorded.".
- Rule_of_three_(statistics) label "Rule of three (statistics)".
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- Rule_of_three_(statistics) isPrimaryTopicOf Rule_of_three_(statistics).