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- Sxy_5'_UTR_element abstract "The Sxy 5' UTR element is an RNA element that controls expression of the sxy gene in H. influenzae. The sxy gene is a transcription factor (also known as TfoX) that regulates competence which is the ability of bacteria to take up DNA from their environment. When the sxy gene is deleted the bacterium loses the ability to express genes in the competence regulon. Cameron et al. recently showed that mutations in the 5' end of the sxy gene lead to hypercompetance. They showed that this region formed an RNA secondary structure that occludes the Shine-Dalgarno sequence. Mutations that interfere with the stability of this secondary structure lead to increased translation of sxy followed by upregulation of the competence regulon.".
- Sxy_5'_UTR_element thumbnail Sxy_structure.JPG?width=300.
- Sxy_5'_UTR_element wikiPageExternalLink RF00632.
- Sxy_5'_UTR_element wikiPageID "18516161".
- Sxy_5'_UTR_element wikiPageRevisionID "605314861".
- Sxy_5'_UTR_element caption "Secondary structure of the sxy 5'-UTR regulatory element".
- Sxy_5'_UTR_element hasPhotoCollection Sxy_5'_UTR_element.
- Sxy_5'_UTR_element name "sxy 5' UTR element".
- Sxy_5'_UTR_element rfam "RF00632".
- Sxy_5'_UTR_element rnaType Cis-regulatory_element.
- Sxy_5'_UTR_element symbol "sxy".
- Sxy_5'_UTR_element taxDomain "Haemophilus influenzae".
- Sxy_5'_UTR_element width "200".
- Sxy_5'_UTR_element subject Category:Cis-regulatory_RNA_elements.
- Sxy_5'_UTR_element comment "The Sxy 5' UTR element is an RNA element that controls expression of the sxy gene in H. influenzae. The sxy gene is a transcription factor (also known as TfoX) that regulates competence which is the ability of bacteria to take up DNA from their environment. When the sxy gene is deleted the bacterium loses the ability to express genes in the competence regulon. Cameron et al. recently showed that mutations in the 5' end of the sxy gene lead to hypercompetance.".
- Sxy_5'_UTR_element label "Sxy 5' UTR element".
- Sxy_5'_UTR_element sameAs m.04f54ng.
- Sxy_5'_UTR_element sameAs Q7659405.
- Sxy_5'_UTR_element sameAs Q7659405.
- Sxy_5'_UTR_element wasDerivedFrom Sxy_5'_UTR_element?oldid=605314861.
- Sxy_5'_UTR_element depiction Sxy_structure.JPG.
- Sxy_5'_UTR_element isPrimaryTopicOf Sxy_5'_UTR_element.