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- Tajima's_D abstract "Tajima's D is a statistical test created by and named after the Japanese researcher Fumio Tajima. The purpose of the test is to distinguish between a DNA sequence evolving randomly ("neutrally") and one evolving under a non-random process, including directional selection or balancing selection, demographic expansion or contraction, genetic hitchhiking, or introgression. A randomly evolving DNA sequence contains mutations with no effect on the fitness and survival of an organism. The randomly evolving mutations are called "neutral", while mutations under selection are "non-neutral". For example, you would expect to find that a mutation which causes prenatal death or severe disease to be under selection. When looking at the human population as a whole, we say that the population frequency of a neutral mutation fluctuates randomly (i.e. the percentage of people in the population with the mutation changes from one generation to the next, and this percentage is equally likely to go up or down) through genetic drift. The strength of genetic drift depends on the population size. If a population is at a constant size with constant mutation rate, the population will reach an equilibrium of gene frequencies. This equilibrium has important properties, including the number of segregating sites , and the number of nucleotide differences between pairs sampled (these are called pairwise differences). To standardize the pairwise differences, the mean or 'average' number of pairwise differences is used. This is simply the sum of the pairwise differences divided by the number of pairs, and is signified by . The purpose of Tajima's test is to identify sequences which do not fit the neutral theory model at equilibrium between mutation and genetic drift. In order to perform the test on a DNA sequence or gene, you need to sequence homologous DNA for at least 3 individuals. Tajima's statistic computes a standardized measure of the total number of segregating sites (these are DNA sites that are polymorphic) in the sampled DNA and the average number of mutations between pairs in the sample. The two quantities whose values are compared are both method of moments estimates of the population genetic parameter theta, and so are expected to equal the same value. If these two numbers only differ by as much as one could reasonably expect by chance, then the null hypothesis of neutrality cannot be rejected. Otherwise, the null hypothesis of neutrality is rejected.".
- Tajima's_D wikiPageExternalLink arlequin3.
- Tajima's_D wikiPageExternalLink tajDsession.txt.
- Tajima's_D wikiPageExternalLink scholar?sourceid=Mozilla-search&q=principles+of+population+genetics+hartl+clark.
- Tajima's_D wikiPageExternalLink www.megasoftware.net.
- Tajima's_D wikiPageExternalLink dnasp.
- Tajima's_D wikiPageExternalLink variscan.
- Tajima's_D wikiPageExternalLink watch?v=wiyay4YMq2A.
- Tajima's_D wikiPageExternalLink neutralitytest.html.
- Tajima's_D wikiPageExternalLink Bio::PopGen::Statistics.
- Tajima's_D wikiPageID "11397248".
- Tajima's_D wikiPageRevisionID "606684845".
- Tajima's_D hasPhotoCollection Tajima's_D.
- Tajima's_D subject Category:DNA.
- Tajima's_D subject Category:Molecular_evolution.
- Tajima's_D subject Category:Statistical_genetics.
- Tajima's_D subject Category:Statistical_tests.
- Tajima's_D type Abstraction100002137.
- Tajima's_D type Cognition100023271.
- Tajima's_D type Experiment105798043.
- Tajima's_D type HigherCognitiveProcess105770664.
- Tajima's_D type Inquiry105797597.
- Tajima's_D type ProblemSolving105796750.
- Tajima's_D type Process105701363.
- Tajima's_D type PsychologicalFeature100023100.
- Tajima's_D type StatisticalTests.
- Tajima's_D type Thinking105770926.
- Tajima's_D type Trial105799212.
- Tajima's_D comment "Tajima's D is a statistical test created by and named after the Japanese researcher Fumio Tajima. The purpose of the test is to distinguish between a DNA sequence evolving randomly ("neutrally") and one evolving under a non-random process, including directional selection or balancing selection, demographic expansion or contraction, genetic hitchhiking, or introgression. A randomly evolving DNA sequence contains mutations with no effect on the fitness and survival of an organism.".
- Tajima's_D label "Tajima's D".
- Tajima's_D label "Tajima's D".
- Tajima's_D sameAs Tajima's_D.
- Tajima's_D sameAs m.02rb475.
- Tajima's_D sameAs Q7676859.
- Tajima's_D sameAs Q7676859.
- Tajima's_D sameAs Tajima's_D.
- Tajima's_D wasDerivedFrom Tajima's_D?oldid=606684845.
- Tajima's_D isPrimaryTopicOf Tajima's_D.