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- 2009921196 contributor B11721209.
- 2009921196 created "c2009.".
- 2009921196 date "2009".
- 2009921196 date "c2009.".
- 2009921196 dateCopyrighted "c2009.".
- 2009921196 description "Includes bibliographical references and index.".
- 2009921196 description "New insights into GPCR function: implications for HTS / R.M. Eglen and T. Reisine -- Screening technologies for G protein-coupled receptors: from HTS to uHTS / M. De los Frailes and E. Diez -- GPCR signaling: understanding the pathway to successful drug discovery / C. Williams and S.J. Hill -- An overview on GPCRs and drug discovery: structure-based drug design and structural biology on GPCRs / K. Lundstrom -- Understanding the ligand-receptor-G protein ternary complex for GPCR drug discovery / V.R. Ratnala and B. Kobilka -- Assay data quality assessment / H. Gubler -- Homology modeling of GPCRs / J. Simms ... [et al.] -- GPCR expression using baculovirus-infected Sf9 cells / A.L. Aloia ... [et al.] -- Radioligand binding assays: application of [(125)I]angiotensin II receptor binding / W.R. Leifert ... [et al.] -- [35S]GTPgammaS binding in G protein-coupled receptor assays / T. Cooper, E.J. McMurchie and W.R. Leifert -- A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery / J. Labrecque, R.S. Wong and S.P. Fricker -- Use of the DiscoveRx Hit hunter cAMPII assay for direct measurement of cAMP in Gs and Gi GPCRs / J. Bradley and D. McLoughlin -- Use of aequorin for G protein-coupled receptor hit identification and compound profiling / S.J. Brough and P. Shah -- BacMam: versatile gene delivery technology for GPCR assays / E.A. Davenport, P. Nuthulaganti and R.S. Ames -- Yeast assays for G protein-coupled receptors / S.J. Dowell and A.J. Brown -- GPCR microspot assays on solid substrates / Y. Fang and J. Lahiri -- Resonant waveguide grating biosensor for whole-cell GPCR assays / Y. Fang, A.M. Ferrie and E. Tran -- FRET-based measurement of GPCR conformational changes / S. Granier ... [et al.] -- FLIPR assays of intracellular calcium in GPCR drug discovery / K.B. Hansen and H. Brauner-Osborne -- Use of fluorescence indicators in receptor ligands / K.G. Harikumar and L.J. Miller -- Application of fluorescence resonance energy transfer techniques to establish ligand-receptor orientation / K.G. Harikumar and L.J. Miller -- Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology / M. Kocan and K.D. Pfleger -- Using reporter gene technologies to detect changes in cAMP as a result of GPCR activation / D.J. Rodrigues and D. McLoughlin -- A quantum dot-labeled ligand-receptor binding assay for G protein-coupled receptors contained in minimally purified membrane nanopatches / J.L. Swift, M.C. Burger and D.T. Cramb -- Xenopus oocyte electrophysiology in GPCR drug discovery / K.B. Hansen and H. Brauner-Osborne -- Immunoprecipitation and phosphorylation of G protein-coupled receptors / W.G. Thomas.".
- 2009921196 extent "xi, 376 p. :".
- 2009921196 identifier "1603273166 (hbk. : alk. paper)".
- 2009921196 identifier "1603273174 (e-ISBN)".
- 2009921196 identifier "9781603273169 (hbk. : alk. paper)".
- 2009921196 identifier "9781603273176 (e-ISBN)".
- 2009921196 identifier 978-1-60327-316-9.
- 2009921196 identifier 978-1-60327-317-6.
- 2009921196 isPartOf "Methods in molecular biology (Clifton, N.J.) ; v. 552.".
- 2009921196 isPartOf "Methods in molecular biology ; 552".
- 2009921196 isPartOf "Springer protocols".
- 2009921196 isPartOf "Springer protocols.".
- 2009921196 issued "2009".
- 2009921196 issued "c2009.".
- 2009921196 language "eng".
- 2009921196 publisher "New York : Humana Press,".
- 2009921196 subject "Arzneimittelforschung swd".
- 2009921196 subject "Drug Discovery Laboratory Manuals.".
- 2009921196 subject "Drug development.".
- 2009921196 subject "G proteins Receptors.".
- 2009921196 subject "G-Proteine swd".
- 2009921196 subject "Pharmacie Recherche. ram".
- 2009921196 subject "Protéines G Récepteurs. ram".
- 2009921196 subject "QP552.G16 G1746 2009".
- 2009921196 subject "QU 25 G1111 2009".
- 2009921196 subject "Receptors, G-Protein-Coupled Laboratory Manuals.".
- 2009921196 subject "Rezeptor swd".
- 2009921196 subject "Screening swd".
- 2009921196 subject "Untersuchungsmethode swd".
- 2009921196 subject "W1 ME9616J v.552 2009".
- 2009921196 subject "Wirkstoff swd".
- 2009921196 tableOfContents "New insights into GPCR function: implications for HTS / R.M. Eglen and T. Reisine -- Screening technologies for G protein-coupled receptors: from HTS to uHTS / M. De los Frailes and E. Diez -- GPCR signaling: understanding the pathway to successful drug discovery / C. Williams and S.J. Hill -- An overview on GPCRs and drug discovery: structure-based drug design and structural biology on GPCRs / K. Lundstrom -- Understanding the ligand-receptor-G protein ternary complex for GPCR drug discovery / V.R. Ratnala and B. Kobilka -- Assay data quality assessment / H. Gubler -- Homology modeling of GPCRs / J. Simms ... [et al.] -- GPCR expression using baculovirus-infected Sf9 cells / A.L. Aloia ... [et al.] -- Radioligand binding assays: application of [(125)I]angiotensin II receptor binding / W.R. Leifert ... [et al.] -- [35S]GTPgammaS binding in G protein-coupled receptor assays / T. Cooper, E.J. McMurchie and W.R. Leifert -- A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery / J. Labrecque, R.S. Wong and S.P. Fricker -- Use of the DiscoveRx Hit hunter cAMPII assay for direct measurement of cAMP in Gs and Gi GPCRs / J. Bradley and D. McLoughlin -- Use of aequorin for G protein-coupled receptor hit identification and compound profiling / S.J. Brough and P. Shah -- BacMam: versatile gene delivery technology for GPCR assays / E.A. Davenport, P. Nuthulaganti and R.S. Ames -- Yeast assays for G protein-coupled receptors / S.J. Dowell and A.J. Brown -- GPCR microspot assays on solid substrates / Y. Fang and J. Lahiri -- Resonant waveguide grating biosensor for whole-cell GPCR assays / Y. Fang, A.M. Ferrie and E. Tran -- FRET-based measurement of GPCR conformational changes / S. Granier ... [et al.] -- FLIPR assays of intracellular calcium in GPCR drug discovery / K.B. Hansen and H. Brauner-Osborne -- Use of fluorescence indicators in receptor ligands / K.G. Harikumar and L.J. Miller -- Application of fluorescence resonance energy transfer techniques to establish ligand-receptor orientation / K.G. Harikumar and L.J. Miller -- Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology / M. Kocan and K.D. Pfleger -- Using reporter gene technologies to detect changes in cAMP as a result of GPCR activation / D.J. Rodrigues and D. McLoughlin -- A quantum dot-labeled ligand-receptor binding assay for G protein-coupled receptors contained in minimally purified membrane nanopatches / J.L. Swift, M.C. Burger and D.T. Cramb -- Xenopus oocyte electrophysiology in GPCR drug discovery / K.B. Hansen and H. Brauner-Osborne -- Immunoprecipitation and phosphorylation of G protein-coupled receptors / W.G. Thomas.".
- 2009921196 title "G protein-coupled receptors in drug discovery / edited by Wayne R. Leifert.".
- 2009921196 type "text".