Matches in DBpedia 2014 for { ?s ?p 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide (W-15) is a potent μ-opioid agonist with a distinctive chemical structure which is not closely related to other established families of opioid drugs. It was invented by chemists Edward Knaus, Brent Warran and Theodore Ondrus in 1981.In animal studies the compound was found to be 5.4 times more potent than morphine in the phenylquinone writhing test when administered subcutaneously.[citation needed] However, due to its structural differences from other opioid drugs it would be difficult to represent as being "substantially similar in chemical structure" to any other controlled drug.It has never been studied in humans, but would be expected to produce effects similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria, constipation, itching and respiratory depression which could be harmful or fatal. Tolerance and dependence are expected to develop rapidly based on the potency of the drug.. }
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- 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide abstract "1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide (W-15) is a potent μ-opioid agonist with a distinctive chemical structure which is not closely related to other established families of opioid drugs. It was invented by chemists Edward Knaus, Brent Warran and Theodore Ondrus in 1981.In animal studies the compound was found to be 5.4 times more potent than morphine in the phenylquinone writhing test when administered subcutaneously.[citation needed] However, due to its structural differences from other opioid drugs it would be difficult to represent as being "substantially similar in chemical structure" to any other controlled drug.It has never been studied in humans, but would be expected to produce effects similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria, constipation, itching and respiratory depression which could be harmful or fatal. Tolerance and dependence are expected to develop rapidly based on the potency of the drug.".