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- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane abstract "RTI-126 ((–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5 times more potent a stimulant than cocaine, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter. RTI-126 has a fast onset of effects and short duration of action, and its pharmacological profile in animals is among the closest to cocaine itself out of all the drugs in the RTI series. Its main application in scientific research has been in studies investigating the influence of pharmacokinetics on the abuse potential of stimulant drugs, with its rapid entry into the brain thought to be a key factor in producing its high propensity for development of dependence in animals.The structurally related compound (–)-2β-(3-methyl-5-isoxazolyl)nortropane is a potent and selective agonist for nicotinic acetylcholine receptors, with twice the potency of nicotine.".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane thumbnail RTI-126.png?width=300.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageID "18655261".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wikiPageRevisionID "549450726".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane c "17".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane casNumber "146659".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane h "21".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane iupacName "-8".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane legalStatus "Temporary Class Drug".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane molecularWeight "283.367".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane n "3".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane o "1".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane smiles "CN2C1CCC2CCC1c3ncon3".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane width "220".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Dopamine_reuptake_inhibitors.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Oxadiazoles.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:RTI_compounds.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Stimulants.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane subject Category:Tropanes.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type Drug.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane type FunctionalSubstance.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane comment "RTI-126 ((–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5 times more potent a stimulant than cocaine, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter.".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane label "(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane".
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs (-)-2%CE%B2-(1,2,4-Oxadiazol-5-methyl)-3%CE%B2-phenyltropane.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs Q4540633.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane sameAs Q4540633.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane wasDerivedFrom (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane?oldid=549450726.
- (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane depiction RTI-126.png.
