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- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate abstract "(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP or HMB-PP) is an intermediate of the non-mevalonate pathway of isoprenoid biosynthesis. The enzyme HMB-PP synthase (GcpE, IspG) catalyzes the conversion of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate (MEcPP) into HMB-PP, and HMB-PP is then converted further to isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) by HMB-PP reductase (LytB, IspH).HMB-PP is an essential metabolite in most pathogenic bacteria including Mycobacterium tuberculosis as well as in malaria parasites, but is absent from the human host.HMB-PP is the physiological activator ("phosphoantigen") for human Vγ9/Vδ2 T cells, the major γδ T cell population in peripheral blood. With a bioactivity of 0.1 nM it is 10,000-10,000,000 times more potent than any other natural compound, such as IPP or alkyl amines.".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate iupacName "(E)-4-hydroxy-3-methylbut-2-enoxy-oxidophosphoryl phosphate".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate thumbnail HMB-PP.PNG?width=300.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate wikiPageID "8399736".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate wikiPageRevisionID "541502831".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate hasPhotoCollection (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagefile "HMB-PP.PNG".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagefile "HMBPP-3D-balls.png".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagename "Ball-and-stick model, shown here as a 3- ion".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagename "Chemical structure of HMB-PP".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagesize "190".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate imagesize "240".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate iupacname "-4".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate name "-4".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate othernames "-4".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate othernames "HDMAPP".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate othernames "HMBDP".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate verifiedrevid "456493945".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate subject Category:Biomolecules.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate subject Category:Hemiterpenes.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate subject Category:Metabolism.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate subject Category:Organophosphates.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate type ChemicalCompound.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate type ChemicalSubstance.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate type ChemicalSubstanceType.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate type ChemicalObject.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate type Thing.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate comment "(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP or HMB-PP) is an intermediate of the non-mevalonate pathway of isoprenoid biosynthesis.".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate label "(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate label "(E)-4-hydroxy-3-méthyl-but-2-ényl-pyrophosphate".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate label "(E)-4-ヒドロキシ-3-メチル-2-ブテニル二リン酸".
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate sameAs (E)-4-hydroxy-3-méthyl-but-2-ényl-pyrophosphate.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate sameAs (E)-4-ヒドロキシ-3-メチル-2-ブテニル二リン酸.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate sameAs m.02724nx.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate sameAs Q2708007.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate sameAs Q2708007.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate wasDerivedFrom (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate?oldid=541502831.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate depiction HMB-PP.PNG.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate isPrimaryTopicOf (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate.
- (E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate name "(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate".
