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- 1,3-Beta-glucan_synthase abstract "1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin.The biosynthesis of disaccharides, oligosaccharides, and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates (EC 2.4.1.-.), and related proteins into distinct sequence-based families has been described. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site . The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and, therefore, form 'clans'.This is the glycosyltransferase 48 family, which consists of various 1,3-beta-glucan synthase components including Gls1, Gls2, and Gls3 from yeast. 1,3-Beta-glucan synthase (EC 2.4.1.34.) also known as callose synthase catalyses the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalysed is:-UDP-glucose + {(1,3)-beta-D-glucosyl}(N) = UDP + {(1,3)-beta-D-glucosyl}(N+1).".
- 1,3-Beta-glucan_synthase ecNumber "2.4.1.34".
- 1,3-Beta-glucan_synthase wikiPageExternalLink www.cazy.org.
- 1,3-Beta-glucan_synthase wikiPageID "12931666".
- 1,3-Beta-glucan_synthase wikiPageRevisionID "588291222".
- 1,3-Beta-glucan_synthase casNumber "9037".
- 1,3-Beta-glucan_synthase cazy "GT48".
- 1,3-Beta-glucan_synthase ecNumber "2.4".
- 1,3-Beta-glucan_synthase hasPhotoCollection 1,3-Beta-glucan_synthase.
- 1,3-Beta-glucan_synthase interpro "IPR003440".
- 1,3-Beta-glucan_synthase iubmbEcNumber "2".
- 1,3-Beta-glucan_synthase name "13".
- 1,3-Beta-glucan_synthase name "Glucan_synthase".
- 1,3-Beta-glucan_synthase pfam "PF02364".
- 1,3-Beta-glucan_synthase pfamClan "CL0111".
- 1,3-Beta-glucan_synthase symbol "Glucan_synthase".
- 1,3-Beta-glucan_synthase subject Category:EC_2.4.1.
- 1,3-Beta-glucan_synthase subject Category:Protein_families.
- 1,3-Beta-glucan_synthase type Biomolecule.
- 1,3-Beta-glucan_synthase type Enzyme.
- 1,3-Beta-glucan_synthase type BiologicalObject.
- 1,3-Beta-glucan_synthase comment "1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin.The biosynthesis of disaccharides, oligosaccharides, and polysaccharides involves the action of hundreds of different glycosyltransferases.".
- 1,3-Beta-glucan_synthase label "1,3-Beta-glucan synthase".
- 1,3-Beta-glucan_synthase label "1,3-beta-glucano sintasi".
- 1,3-Beta-glucan_synthase sameAs 1,3-beta-glucano_sintasi.
- 1,3-Beta-glucan_synthase sameAs m.02z0cmb.
- 1,3-Beta-glucan_synthase sameAs Q3596746.
- 1,3-Beta-glucan_synthase sameAs Q3596746.
- 1,3-Beta-glucan_synthase wasDerivedFrom 1,3-Beta-glucan_synthase?oldid=588291222.
- 1,3-Beta-glucan_synthase isPrimaryTopicOf 1,3-Beta-glucan_synthase.
- 1,3-Beta-glucan_synthase name "1,3-Beta-glucan synthase".