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- 14-Methoxymetopon abstract "14-Methoxymetopon is an opiate analogue developed by a team led by Professor Helmut Schmidhammer at the University of Insbruck in the mid 1990s. It is a derivative of metopon in which a methoxy group has been inserted at the 14-position. It is a highly potent analgesic drug that is around 500x stronger than morphine when administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine. It binds strongly to the μ-opioid receptor and activates it to a greater extent than most similar opioid drugs. This produces an unusual pharmacological profile, and although 14-methoxymetopon acts as a potent μ-opioid full agonist in regards to some effects such as analgesia, a ceiling effect is seen on other effects such as constipation and respiratory depression which is believed to involve interaction with the κ-opioid receptor".
- 14-Methoxymetopon casNumber "131575-03-6".
- 14-Methoxymetopon iupacName "3-Hydroxy-14-methoxy-5,17-dimethyl-7,8-dihydro-4,5α-epoxy-morphinan-6-one".
- 14-Methoxymetopon pubchem "5486940".
- 14-Methoxymetopon thumbnail 14-methoxymetopon.svg?width=300.
- 14-Methoxymetopon wikiPageID "17016406".
- 14-Methoxymetopon wikiPageRevisionID "556297923".
- 14-Methoxymetopon c "19".
- 14-Methoxymetopon casNumber "131575".
- 14-Methoxymetopon chembl "326684".
- 14-Methoxymetopon chemspiderid "4589140".
- 14-Methoxymetopon h "23".
- 14-Methoxymetopon hasPhotoCollection 14-Methoxymetopon.
- 14-Methoxymetopon inchi "1".
- 14-Methoxymetopon inchikey "DENICFHULARDRG-WEZQJLTABW".
- 14-Methoxymetopon iupacName "3".
- 14-Methoxymetopon molecularWeight "329.39".
- 14-Methoxymetopon n "1".
- 14-Methoxymetopon o "4".
- 14-Methoxymetopon pubchem "5486940".
- 14-Methoxymetopon smiles "C[C@]12CCC[C@@]3OC".
- 14-Methoxymetopon stdinchi "1".
- 14-Methoxymetopon stdinchikey "DENICFHULARDRG-WEZQJLTASA-N".
- 14-Methoxymetopon synonyms "14".
- 14-Methoxymetopon verifiedfields "changed".
- 14-Methoxymetopon verifiedrevid "477209012".
- 14-Methoxymetopon watchedfields "changed".
- 14-Methoxymetopon width "220".
- 14-Methoxymetopon subject Category:Ethers.
- 14-Methoxymetopon subject Category:Ketones.
- 14-Methoxymetopon subject Category:Morphinans.
- 14-Methoxymetopon subject Category:Mu-opioid_agonists.
- 14-Methoxymetopon subject Category:Opioids.
- 14-Methoxymetopon subject Category:Phenols.
- 14-Methoxymetopon subject Category:Semisynthetic_opioids.
- 14-Methoxymetopon type Drug.
- 14-Methoxymetopon type DrugProduct.
- 14-Methoxymetopon type FunctionalSubstance.
- 14-Methoxymetopon comment "14-Methoxymetopon is an opiate analogue developed by a team led by Professor Helmut Schmidhammer at the University of Insbruck in the mid 1990s. It is a derivative of metopon in which a methoxy group has been inserted at the 14-position. It is a highly potent analgesic drug that is around 500x stronger than morphine when administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine.".
- 14-Methoxymetopon label "14-Methoxymetopon".
- 14-Methoxymetopon sameAs m.0415n_8.
- 14-Methoxymetopon sameAs Q4549584.
- 14-Methoxymetopon sameAs Q4549584.
- 14-Methoxymetopon wasDerivedFrom 14-Methoxymetopon?oldid=556297923.
- 14-Methoxymetopon depiction 14-methoxymetopon.svg.
- 14-Methoxymetopon isPrimaryTopicOf 14-Methoxymetopon.