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- 3-alpha-HSD abstract "3α-hydroxysteroid dehydrogenase (3α-HSD), also known as aldo-keto reductase family 1 member C4, is an enzyme that in humans is encoded by the AKR1C4 gene. It is known to catalyze the reversible conversion of 3α-androstanediol (5α-androstane-3α,17β-diol) to dihydrotestosterone (DHT) (5α-androstan-17β-ol-3-one) and vice-versa.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.".
- 3-alpha-HSD entrezgene "1109".
- 3-alpha-HSD wikiPageID "14800502".
- 3-alpha-HSD wikiPageRevisionID "589764720".
- 3-alpha-HSD hasPhotoCollection 3-alpha-HSD.
- 3-alpha-HSD requireManualInspection "no".
- 3-alpha-HSD updateCitations "yes".
- 3-alpha-HSD updatePage "yes".
- 3-alpha-HSD updateProteinBox "yes".
- 3-alpha-HSD updateSummary "no".
- 3-alpha-HSD subject Category:EC_1.1.
- 3-alpha-HSD type Biomolecule.
- 3-alpha-HSD type Protein.
- 3-alpha-HSD type BiologicalObject.
- 3-alpha-HSD comment "3α-hydroxysteroid dehydrogenase (3α-HSD), also known as aldo-keto reductase family 1 member C4, is an enzyme that in humans is encoded by the AKR1C4 gene. It is known to catalyze the reversible conversion of 3α-androstanediol (5α-androstane-3α,17β-diol) to dihydrotestosterone (DHT) (5α-androstan-17β-ol-3-one) and vice-versa.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.".
- 3-alpha-HSD label "3-alpha-HSD".
- 3-alpha-HSD sameAs m.03gyfrs.
- 3-alpha-HSD sameAs Q4634197.
- 3-alpha-HSD sameAs Q4634197.
- 3-alpha-HSD wasDerivedFrom 3-alpha-HSD?oldid=589764720.
- 3-alpha-HSD isPrimaryTopicOf 3-alpha-HSD.