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- 5α-Androstane-3β,17β-diol abstract "5α-Androstane-3β,17β-diol, also called 3β-androstanediol, and often shortened to 3β-diol, is an endogenous steroid hormone. It is a 5α-reduced and 17β-hydroxylated metabolite of dehydroepiandrosterone (DHEA) as well as a 3β-hydroxylated metabolite of dihydrotestosterone (DHT). Similarly to DHEA, 3β-diol is a high-affinity full agonist of the ERβ, and hence, an estrogen. In contrast, it does not bind to the androgen receptor. As a result of activation of the ERβ, 3β-diol has antiproliferative effects against prostate cancer cells and proliferative effects on breast cancer cells.A determination of the circulating levels of 3β-diol in humans found concentrations of 239 ± 76 pg/ml and 82 ± 45 pg/ml of the compound in normal male and female serum, respectively.".
- 5α-Androstane-3β,17β-diol thumbnail Androstanediol.png?width=300.
- 5α-Androstane-3β,17β-diol wikiPageID "35965214".
- 5α-Androstane-3β,17β-diol wikiPageRevisionID "589801236".
- 5α-Androstane-3β,17β-diol imagefile "Androstanediol.png".
- 5α-Androstane-3β,17β-diol iupacname "-Androstane-3,17-diol".
- 5α-Androstane-3β,17β-diol subject Category:Androgens.
- 5α-Androstane-3β,17β-diol subject Category:Beta-estrogen_agonists.
- 5α-Androstane-3β,17β-diol subject Category:Endogenous_androgenic_substances.
- 5α-Androstane-3β,17β-diol subject Category:Estrogens.
- 5α-Androstane-3β,17β-diol subject Category:Steroids.
- 5α-Androstane-3β,17β-diol type ChemicalCompound.
- 5α-Androstane-3β,17β-diol type ChemicalSubstance.
- 5α-Androstane-3β,17β-diol type ChemicalObject.
- 5α-Androstane-3β,17β-diol type Thing.
- 5α-Androstane-3β,17β-diol comment "5α-Androstane-3β,17β-diol, also called 3β-androstanediol, and often shortened to 3β-diol, is an endogenous steroid hormone. It is a 5α-reduced and 17β-hydroxylated metabolite of dehydroepiandrosterone (DHEA) as well as a 3β-hydroxylated metabolite of dihydrotestosterone (DHT). Similarly to DHEA, 3β-diol is a high-affinity full agonist of the ERβ, and hence, an estrogen. In contrast, it does not bind to the androgen receptor.".
- 5α-Androstane-3β,17β-diol label "5α-Androstane-3β,17β-diol".
- 5α-Androstane-3β,17β-diol sameAs 5%CE%B1-Androstane-3%CE%B2,17%CE%B2-diol.
- 5α-Androstane-3β,17β-diol sameAs Q4641516.
- 5α-Androstane-3β,17β-diol sameAs Q4641516.
- 5α-Androstane-3β,17β-diol wasDerivedFrom 5α-Androstane-3β,17β-diol?oldid=589801236.
- 5α-Androstane-3β,17β-diol depiction Androstanediol.png.