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- 6-Methylenedihydrodesoxymorphine abstract "6-Methylenedihydrodesoxymorphine (6-MDDM) is an opiate analogue that is a derivative of hydromorphone, where the 6-ketone group has been replaced by a methylene group. It has sedative and analgesic effects.6-Methylenedihydrodesoxymorphine is a potent μ-opioid agonist, 80x stronger than morphine. Compared to morphine it has a faster onset of action and similar duration of effects. It produces around the same degree of respiratory depression as morphine, but less inhibition of gastrointestinal motility. Animal studies show it to be a potent analgesic which produces significant analgesic effects even at low doses while inducing comparatively few side effects, however it has never been developed for medical use in humans.6-Methylenedihydrodesoxymorphine is synthesised in two steps; first a Wittig reaction is used, reacting hydrocodone with methylenetriphenylphosphorane and an alkyl lithium reagent in diethyl ether to form 6-Methylenedihydrodesoxycodeine. The 3-methoxy group is then cleaved to hydroxy, by reaction with pyridine. The second step tends to be incomplete and often gives fairly low yields, but these can be improved by changing the reaction conditions.".
- 6-Methylenedihydrodesoxymorphine casNumber "3414-84-4".
- 6-Methylenedihydrodesoxymorphine iupacName "4,5-α-Epoxy-17-methyl-6-methylenemorphinan-3-ol".
- 6-Methylenedihydrodesoxymorphine pubchem "5492874".
- 6-Methylenedihydrodesoxymorphine thumbnail 6-Methylenedihydrodesoxymorphine.svg?width=300.
- 6-Methylenedihydrodesoxymorphine wikiPageID "14280290".
- 6-Methylenedihydrodesoxymorphine wikiPageRevisionID "558417806".
- 6-Methylenedihydrodesoxymorphine c "18".
- 6-Methylenedihydrodesoxymorphine casNumber "3414".
- 6-Methylenedihydrodesoxymorphine chemspiderid "4591200".
- 6-Methylenedihydrodesoxymorphine h "21".
- 6-Methylenedihydrodesoxymorphine hasPhotoCollection 6-Methylenedihydrodesoxymorphine.
- 6-Methylenedihydrodesoxymorphine inchi "1".
- 6-Methylenedihydrodesoxymorphine inchikey "LBCZKDPFDXFDTN-GGNLRSJOBK".
- 6-Methylenedihydrodesoxymorphine iupacName "45".
- 6-Methylenedihydrodesoxymorphine molecularWeight "283.36".
- 6-Methylenedihydrodesoxymorphine n "1".
- 6-Methylenedihydrodesoxymorphine o "2".
- 6-Methylenedihydrodesoxymorphine pubchem "5492874".
- 6-Methylenedihydrodesoxymorphine smiles "Oc2c1O[C@H]5\CCC[C@H]4[C@@H]3NC".
- 6-Methylenedihydrodesoxymorphine stdinchi "1".
- 6-Methylenedihydrodesoxymorphine stdinchikey "LBCZKDPFDXFDTN-GGNLRSJOSA-N".
- 6-Methylenedihydrodesoxymorphine synonyms "6".
- 6-Methylenedihydrodesoxymorphine verifiedfields "changed".
- 6-Methylenedihydrodesoxymorphine verifiedrevid "477226081".
- 6-Methylenedihydrodesoxymorphine watchedfields "changed".
- 6-Methylenedihydrodesoxymorphine width "200".
- 6-Methylenedihydrodesoxymorphine subject Category:Morphinans.
- 6-Methylenedihydrodesoxymorphine subject Category:Mu-opioid_agonists.
- 6-Methylenedihydrodesoxymorphine subject Category:Phenols.
- 6-Methylenedihydrodesoxymorphine subject Category:Semisynthetic_opioids.
- 6-Methylenedihydrodesoxymorphine type Drug.
- 6-Methylenedihydrodesoxymorphine type DrugProduct.
- 6-Methylenedihydrodesoxymorphine type FunctionalSubstance.
- 6-Methylenedihydrodesoxymorphine comment "6-Methylenedihydrodesoxymorphine (6-MDDM) is an opiate analogue that is a derivative of hydromorphone, where the 6-ketone group has been replaced by a methylene group. It has sedative and analgesic effects.6-Methylenedihydrodesoxymorphine is a potent μ-opioid agonist, 80x stronger than morphine. Compared to morphine it has a faster onset of action and similar duration of effects.".
- 6-Methylenedihydrodesoxymorphine label "6-Methylenedihydrodesoxymorphine".
- 6-Methylenedihydrodesoxymorphine sameAs m.03c_40m.
- 6-Methylenedihydrodesoxymorphine sameAs Q429449.
- 6-Methylenedihydrodesoxymorphine sameAs Q429449.
- 6-Methylenedihydrodesoxymorphine wasDerivedFrom 6-Methylenedihydrodesoxymorphine?oldid=558417806.
- 6-Methylenedihydrodesoxymorphine depiction 6-Methylenedihydrodesoxymorphine.svg.
- 6-Methylenedihydrodesoxymorphine isPrimaryTopicOf 6-Methylenedihydrodesoxymorphine.