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- A-372,159 abstract "A-372,159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM. It has been found to produce anorectic effects in animal studies and produced significant weight loss in rats with no development of tolerance or serious side effects.".
- A-372,159 iupacName "(11S,16R)-3-[4-(propan-2-yloxy)-2-(trifluoromethyl)phenyl]-6-oxa-10,14-diazatetracyclo[8.6.1.05,17.011,16]heptadeca-1,3,5(17)-triene".
- A-372,159 thumbnail A-372,159_structure.png?width=300.
- A-372,159 wikiPageID "20289211".
- A-372,159 wikiPageRevisionID "545500949".
- A-372,159 c "24".
- A-372,159 chemspiderid "9605283".
- A-372,159 f "3".
- A-372,159 h "27".
- A-372,159 hasPhotoCollection A-372,159.
- A-372,159 inchi "1".
- A-372,159 inchikey "LADKOBQJOCFCQU-FPOVZHCZBZ".
- A-372,159 iupacName "-3".
- A-372,159 molecularWeight "432.478".
- A-372,159 n "2".
- A-372,159 o "2".
- A-372,159 smiles "FCc2ccccc2-ccc1c3N4C5CCNCC15".
- A-372,159 stdinchi "1".
- A-372,159 stdinchikey "LADKOBQJOCFCQU-FPOVZHCZSA-N".
- A-372,159 verifiedrevid "399345932".
- A-372,159 width "220".
- A-372,159 subject Category:Nitrogen_heterocycles.
- A-372,159 subject Category:Organofluorides.
- A-372,159 subject Category:Oxygen_heterocycles.
- A-372,159 subject Category:Phenol_ethers.
- A-372,159 subject Category:Serotonin_receptor_agonists.
- A-372,159 type Drug.
- A-372,159 type DrugProduct.
- A-372,159 type FunctionalSubstance.
- A-372,159 comment "A-372,159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM. It has been found to produce anorectic effects in animal studies and produced significant weight loss in rats with no development of tolerance or serious side effects.".
- A-372,159 label "A-372,159".
- A-372,159 sameAs m.04zzk9w.
- A-372,159 sameAs Q4646870.
- A-372,159 sameAs Q4646870.
- A-372,159 wasDerivedFrom A-372,159?oldid=545500949.
- A-372,159 depiction A-372,159_structure.png.
- A-372,159 isPrimaryTopicOf A-372,159.