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- A-412,997 abstract "A-412,997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype, with significantly improved selectivity over older D4-preferring compounds such as PD-168,077 and CP-226,269. In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate, but without producing place preference or other signs of abuse liability. Also unlike other dopamine agonists, selective D4 agonists do not cause side effects such as sedation and nausea, and so might have advantages over older dopamine agonist drugs.".
- A-412,997 iupacName "N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide".
- A-412,997 pubchem "10425450".
- A-412,997 thumbnail A-412,997.png?width=300.
- A-412,997 wikiPageID "17504769".
- A-412,997 wikiPageRevisionID "589910414".
- A-412,997 c "19".
- A-412,997 chembl "375596".
- A-412,997 chemspiderid "8600878".
- A-412,997 h "23".
- A-412,997 hasPhotoCollection A-412,997.
- A-412,997 inchi "1".
- A-412,997 inchikey "JFCDMGGMCUKHST-UHFFFAOYAU".
- A-412,997 iupacName "N--2-acetamide".
- A-412,997 molecularWeight "309.405".
- A-412,997 n "3".
- A-412,997 o "1".
- A-412,997 pubchem "10425450".
- A-412,997 smiles "c3cccNCCN2CCCc1ccccn1".
- A-412,997 stdinchi "1".
- A-412,997 stdinchikey "JFCDMGGMCUKHST-UHFFFAOYSA-N".
- A-412,997 verifiedrevid "477234844".
- A-412,997 subject Category:Acetanilides.
- A-412,997 subject Category:Dopamine_agonists.
- A-412,997 subject Category:Piperidines.
- A-412,997 subject Category:Pyridines.
- A-412,997 type Drug.
- A-412,997 type DrugProduct.
- A-412,997 type FunctionalSubstance.
- A-412,997 comment "A-412,997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype, with significantly improved selectivity over older D4-preferring compounds such as PD-168,077 and CP-226,269. In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate, but without producing place preference or other signs of abuse liability.".
- A-412,997 label "A-412,997".
- A-412,997 sameAs m.04cy776.
- A-412,997 sameAs Q4646874.
- A-412,997 sameAs Q4646874.
- A-412,997 wasDerivedFrom A-412,997?oldid=589910414.
- A-412,997 depiction A-412,997.png.
- A-412,997 isPrimaryTopicOf A-412,997.