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- ABCG8 abstract "ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.".
- ABCG8 entrezgene "64241".
- ABCG8 wikiPageID "14769679".
- ABCG8 wikiPageRevisionID "589913773".
- ABCG8 hasPhotoCollection ABCG8.
- ABCG8 requireManualInspection "no".
- ABCG8 summaryText "The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies . This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.".
- ABCG8 updateCitations "no".
- ABCG8 updatePage "yes".
- ABCG8 updateProteinBox "yes".
- ABCG8 updateSummary "yes".
- ABCG8 subject Category:ABC_transporters.
- ABCG8 type Biomolecule.
- ABCG8 type Protein.
- ABCG8 type BiologicalObject.
- ABCG8 comment "ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily.".
- ABCG8 label "ABCG8".
- ABCG8 sameAs m.03gxcw3.
- ABCG8 sameAs Q4650094.
- ABCG8 sameAs Q4650094.
- ABCG8 sameAs ABCG8.
- ABCG8 wasDerivedFrom ABCG8?oldid=589913773.
- ABCG8 isPrimaryTopicOf ABCG8.