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- ABT-418 abstract "ABT-418 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors. It binds with high affinity to the α4β2, α2β2 and α7 subtypes, but not to the α3β4 subtype. It has nootropic, neuroprotective and anxiolytic effects, and has been researched for treatment of both Alzheimer's disease and more recently ADHD. ABT-418 was reasonably effective for both applications and fairly well tolerated, but produced some side effects, principally nausea, and it is unclear whether ABT-418 itself will proceed to clinical development or if another similar drug will be used instead.".
- ABT-418 casNumber "147402-53-7".
- ABT-418 iupacName "3-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,2-oxazole".
- ABT-418 pubchem "119380".
- ABT-418 thumbnail ABT-418.png?width=300.
- ABT-418 wikiPageID "17714359".
- ABT-418 wikiPageRevisionID "590008370".
- ABT-418 c "9".
- ABT-418 casNumber "147402".
- ABT-418 chembl "274525".
- ABT-418 chemspiderid "106627".
- ABT-418 h "14".
- ABT-418 hasPhotoCollection ABT-418.
- ABT-418 inchi "1".
- ABT-418 inchikey "ILLGYRJAYAAAEW-QMMMGPOBBM".
- ABT-418 iupacName "3".
- ABT-418 molecularWeight "166.22".
- ABT-418 n "2".
- ABT-418 o "1".
- ABT-418 pubchem "119380".
- ABT-418 smiles "CC1=NOC[C@@H]2CCCN2C".
- ABT-418 stdinchi "1".
- ABT-418 stdinchikey "ILLGYRJAYAAAEW-QMMMGPOBSA-N".
- ABT-418 verifiedfields "changed".
- ABT-418 verifiedrevid "477235109".
- ABT-418 width "240".
- ABT-418 subject Category:Isoxazoles.
- ABT-418 subject Category:Nicotinic_agonists.
- ABT-418 subject Category:Nootropics.
- ABT-418 subject Category:Pyrrolidines.
- ABT-418 subject Category:Stimulants.
- ABT-418 type Drug.
- ABT-418 type DrugProduct.
- ABT-418 type FunctionalSubstance.
- ABT-418 comment "ABT-418 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors. It binds with high affinity to the α4β2, α2β2 and α7 subtypes, but not to the α3β4 subtype. It has nootropic, neuroprotective and anxiolytic effects, and has been researched for treatment of both Alzheimer's disease and more recently ADHD.".
- ABT-418 label "ABT-418".
- ABT-418 sameAs m.047d662.
- ABT-418 sameAs Q4650418.
- ABT-418 sameAs Q4650418.
- ABT-418 wasDerivedFrom ABT-418?oldid=590008370.
- ABT-418 depiction ABT-418.png.
- ABT-418 isPrimaryTopicOf ABT-418.