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- ABT-450 abstract "ABT-450 is an acylsulfonamide inhibitor of the NS3-4A serine protease manufactured by Abbott Laboratories that shows promising results as a treatment of hepatitis C. When given in combination with ritonavir and ribavirin for 12 weeks, the rate of sustained virologic response at 24 weeks after treatment has been estimated to be 95% for those with hepatitis C virus genotype 1. Resistance to treatment with ABT-450 is uncommon, because it targets the binding site, but has been seen to arise due to mutations at positions 155 and 168 in NS3.p. 248".
- ABT-450 wikiPageID "42480333".
- ABT-450 wikiPageRevisionID "606351878".
- ABT-450 subject Category:Hepatitis_C.
- ABT-450 subject Category:Molecular_biology.
- ABT-450 subject Category:Protease_inhibitors.
- ABT-450 comment "ABT-450 is an acylsulfonamide inhibitor of the NS3-4A serine protease manufactured by Abbott Laboratories that shows promising results as a treatment of hepatitis C. When given in combination with ritonavir and ribavirin for 12 weeks, the rate of sustained virologic response at 24 weeks after treatment has been estimated to be 95% for those with hepatitis C virus genotype 1.".
- ABT-450 label "ABT-450".
- ABT-450 sameAs ABT-450.
- ABT-450 sameAs m.010fcv_x.
- ABT-450 sameAs Q16824572.
- ABT-450 sameAs Q16824572.
- ABT-450 wasDerivedFrom ABT-450?oldid=606351878.
- ABT-450 isPrimaryTopicOf ABT-450.