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- ACTL6B abstract "Actin-like protein 6B is a protein that in humans is encoded by the ACTL6B gene.The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.".
- ACTL6B entrezgene "51412".
- ACTL6B wikiPageID "15072948".
- ACTL6B wikiPageRevisionID "597020931".
- ACTL6B hasPhotoCollection ACTL6B.
- ACTL6B requireManualInspection "no".
- ACTL6B summaryText "The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.".
- ACTL6B updateCitations "yes".
- ACTL6B updatePage "yes".
- ACTL6B updateProteinBox "yes".
- ACTL6B updateSummary "yes".
- ACTL6B subject Category:Human_proteins.
- ACTL6B type Biomolecule.
- ACTL6B type Protein.
- ACTL6B type BiologicalObject.
- ACTL6B comment "Actin-like protein 6B is a protein that in humans is encoded by the ACTL6B gene.The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling.".
- ACTL6B label "ACTL6B".
- ACTL6B sameAs m.03hgmj2.
- ACTL6B sameAs Q4650846.
- ACTL6B sameAs Q4650846.
- ACTL6B wasDerivedFrom ACTL6B?oldid=597020931.
- ACTL6B isPrimaryTopicOf ACTL6B.