Matches in DBpedia 2014 for { <http://dbpedia.org/resource/AKT2> ?p ?o. }
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- AKT2 abstract "RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins. Mice lacking Akt2 have a normal body mass, but display a profound diabetic phenotype, indicating that Akt2 plays a key role in signal transduction downstream of the insulin receptor. Mice lacking Akt2 show worse outcome in breast cancer initaited by the large T antigen as well as the neu oncogene.".
- AKT2 entrezgene "208".
- AKT2 wikiPageID "14117935".
- AKT2 wikiPageRevisionID "602991192".
- AKT2 hasPhotoCollection AKT2.
- AKT2 requireManualInspection "no".
- AKT2 summaryText "This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins. Mice lacking Akt2 have a normal body mass, but display a profound diabetic phenotype, indicating that Akt2 plays a key role in signal transduction downstream of the insulin receptor. Mice lacking Akt2 show worse outcome in breast cancer initaited by the large T antigen as well as the neu oncogene.".
- AKT2 updateCitations "yes".
- AKT2 updatePage "yes".
- AKT2 updateProteinBox "yes".
- AKT2 updateSummary "yes".
- AKT2 type Biomolecule.
- AKT2 type Protein.
- AKT2 type BiologicalObject.
- AKT2 comment "RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers.".
- AKT2 label "AKT2".
- AKT2 sameAs AKT2.
- AKT2 sameAs m.03cv4sb.
- AKT2 sameAs Q4652205.
- AKT2 sameAs Q4652205.
- AKT2 sameAs AKT2.
- AKT2 wasDerivedFrom AKT2?oldid=602991192.
- AKT2 isPrimaryTopicOf AKT2.