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- AM-630 abstract "AM-630 (6-Iodopravadoline) is a drug that acts as a potent and selective inverse agonist for the cannabinoid receptor CB2, with a Ki of 32.1nM at CB2 and 165x selectivity over CB1, at which it acted as a weak partial agonist. It is used in the study of CB2 mediated responses and has been used to investigate the possible role of CB2 receptors in the brain. AM-630 is significant as one of the first indole derived cannabinoid ligands substituted on the 6-position of the indole ring, a position that has subsequently been found to be important in determining affinity and efficacy at both the CB1 and CB2 receptors, and has led to the development of a large number of related derivatives.".
- AM-630 casNumber "164178-33-0".
- AM-630 iupacName "1-[2-(morpholin-4-yl)ethyl]-2-methyl-3-(4-methoxybenzoyl)-6-iodoindole".
- AM-630 pubchem "4302963".
- AM-630 thumbnail AM-630_structure.png?width=300.
- AM-630 wikiPageID "30438930".
- AM-630 wikiPageRevisionID "590552979".
- AM-630 c "23".
- AM-630 casNumber "164178".
- AM-630 chembl "181633".
- AM-630 chemspiderid "3508738".
- AM-630 h "25".
- AM-630 hasPhotoCollection AM-630.
- AM-630 i "1".
- AM-630 iupacName "1".
- AM-630 molecularWeight "504.36".
- AM-630 n "2".
- AM-630 o "3".
- AM-630 pubchem "4302963".
- AM-630 smiles "C4COCCN4CCnc2ccccc2c1Cc3ccccc3".
- AM-630 stdinchi "1".
- AM-630 stdinchikey "JHOTYHDSLIUKCJ-UHFFFAOYSA-N".
- AM-630 verifiedfields "changed".
- AM-630 verifiedrevid "477235883".
- AM-630 width "200".
- AM-630 subject Category:AM_cannabinoids.
- AM-630 subject Category:Aminoalkylindoles.
- AM-630 subject Category:Benzoylindoles.
- AM-630 subject Category:Cannabinoids.
- AM-630 subject Category:Designer_drugs.
- AM-630 subject Category:Morpholines.
- AM-630 subject Category:Organoiodides.
- AM-630 type Drug.
- AM-630 type FunctionalSubstance.
- AM-630 comment "AM-630 (6-Iodopravadoline) is a drug that acts as a potent and selective inverse agonist for the cannabinoid receptor CB2, with a Ki of 32.1nM at CB2 and 165x selectivity over CB1, at which it acted as a weak partial agonist. It is used in the study of CB2 mediated responses and has been used to investigate the possible role of CB2 receptors in the brain.".
- AM-630 label "AM-630".
- AM-630 sameAs m.0g5r6q3.
- AM-630 sameAs Q4652499.
- AM-630 sameAs Q4652499.
- AM-630 wasDerivedFrom AM-630?oldid=590552979.
- AM-630 depiction AM-630_structure.png.
- AM-630 isPrimaryTopicOf AM-630.