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- AM-938 abstract "AM-938 is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxyprop-1-ynyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-938 represents a hybrid structure between the classical and nonclassical cannabinoid families, with the 6-hydroxyalkyl chain rigidified with a triple bond. This gives AM-938 a greater degree of selectivity, so while it is still a potent agonist at both CB1 and CB2, it is reasonably selective for CB2, with a Ki of 0.3nM at CB2 and 1.2nM at CB1, a selectivity of around 4x.".
- AM-938 iupacName "(6S,6aR,9R,10aR)-9-(hydroxymethyl)-6-(3-hydroxyprop-1-ynyl)-6-".
- AM-938 pubchem "10646208".
- AM-938 thumbnail AM-938.png?width=300.
- AM-938 wikiPageID "17361788".
- AM-938 wikiPageRevisionID "480558829".
- AM-938 c "27".
- AM-938 chemspiderid "8821567".
- AM-938 h "40".
- AM-938 hasPhotoCollection AM-938.
- AM-938 inchi "1".
- AM-938 inchikey "FFRHKSZKZQWCOY-UOTIDGTBBE".
- AM-938 iupacName "-9".
- AM-938 molecularWeight "428.603".
- AM-938 o "4".
- AM-938 pubchem "10646208".
- AM-938 smiles "OCC#CC3C1CCCCC1c2cccCCCCCCC".
- AM-938 smiles "Oc2ccCCCCCCC".
- AM-938 stdinchi "1".
- AM-938 stdinchikey "FFRHKSZKZQWCOY-UOTIDGTBSA-N".
- AM-938 verifiedrevid "448104384".
- AM-938 width "240".
- AM-938 subject Category:AM_cannabinoids.
- AM-938 subject Category:Alcohols.
- AM-938 subject Category:Benzochromenes.
- AM-938 subject Category:Cannabinoids.
- AM-938 subject Category:Phenols.
- AM-938 type Drug.
- AM-938 type DrugProduct.
- AM-938 type FunctionalSubstance.
- AM-938 comment "AM-938 is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxyprop-1-ynyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-938 represents a hybrid structure between the classical and nonclassical cannabinoid families, with the 6-hydroxyalkyl chain rigidified with a triple bond.".
- AM-938 label "AM-938".
- AM-938 sameAs m.043jlm8.
- AM-938 sameAs Q4652508.
- AM-938 sameAs Q4652508.
- AM-938 wasDerivedFrom AM-938?oldid=480558829.
- AM-938 depiction AM-938.png.
- AM-938 isPrimaryTopicOf AM-938.
