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- AP-1_transcription_factor abstract "In the field of molecular biology, the activator protein 1 (AP-1) is a transcription factor which is a heterodimeric protein composed of proteins belonging to the c-Fos, c-Jun, ATF and JDP families. It regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections. AP-1 in turn controls a number of cellular processes including differentiation, proliferation, and apoptosis.AP-1 upregulates transcription of genes containing the TPA DNA response element (TRE; 5'-TGAG/CTCA-3'). AP-1 binds to this DNA sequence via a basic amino acid region, while the dimeric structure is formed by a leucine zipper. ".
- AP-1_transcription_factor thumbnail 1FOS.png?width=300.
- AP-1_transcription_factor wikiPageExternalLink JUNID151.html.
- AP-1_transcription_factor wikiPageExternalLink MB_cgi.
- AP-1_transcription_factor wikiPageExternalLink MB_cgi?mode=&term=Transcription+Factor+AP-1.
- AP-1_transcription_factor wikiPageID "9956291".
- AP-1_transcription_factor wikiPageRevisionID "590598276".
- AP-1_transcription_factor activatedBy "PDTC, IE1, JNK, RIP2, TPA, PDCD4, KSHV, MAPK, Serralysin, PRL, K15, Alpha lipoic acid, Phorbol esters, Cytokine,".
- AP-1_transcription_factor activates "cAMP, IL-2, CREB, WEE1, OPN, RD, MMP, calpain-2, G1-Cyclin–dependent Kinases, BMP-4, H1 receptor, cyclin D1, GC-A, TGF-b, NOTCH4, Blimp-1, FasL, TNF-a, c-jun, Bcl-xl, ECs, miR-21, Cox-2, PtdInsP2, tissue factor, HMG-I/Y, PTH, TPA-response element, Gap-43 protein, hMT IIA, TGF-B1, IL-8, IL-4, IL-5, GM-CSF, hGSTP1, Egr-1, Fibronectin,".
- AP-1_transcription_factor hasPhotoCollection AP-1_transcription_factor.
- AP-1_transcription_factor inhibitedBy "MIF, BATF".
- AP-1_transcription_factor inhibits "PAI-1, Collagen, HNF-1, Osteocalcin,".
- AP-1_transcription_factor subject Category:Transcription_factors.
- AP-1_transcription_factor comment "In the field of molecular biology, the activator protein 1 (AP-1) is a transcription factor which is a heterodimeric protein composed of proteins belonging to the c-Fos, c-Jun, ATF and JDP families. It regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.".
- AP-1_transcription_factor label "AP-1 transcription factor".
- AP-1_transcription_factor label "AP-1".
- AP-1_transcription_factor label "AP-1".
- AP-1_transcription_factor label "Factor de transcripción AP-1".
- AP-1_transcription_factor sameAs Factor_de_transcripción_AP-1.
- AP-1_transcription_factor sameAs AP-1.
- AP-1_transcription_factor sameAs AP-1.
- AP-1_transcription_factor sameAs AP-1.
- AP-1_transcription_factor sameAs m.02py1jg.
- AP-1_transcription_factor sameAs Q3270441.
- AP-1_transcription_factor sameAs Q3270441.
- AP-1_transcription_factor wasDerivedFrom AP-1_transcription_factor?oldid=590598276.
- AP-1_transcription_factor depiction 1FOS.png.
- AP-1_transcription_factor isPrimaryTopicOf AP-1_transcription_factor.