Matches in DBpedia 2014 for { <http://dbpedia.org/resource/APBB1> ?p ?o. }
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- APBB1 abstract "Amyloid beta A4 precursor protein-binding family B member 1 is a protein that in humans is encoded by the APBB1 gene.The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.".
- APBB1 entrezgene "322".
- APBB1 wikiPageID "14753789".
- APBB1 wikiPageRevisionID "603295006".
- APBB1 hasPhotoCollection APBB1.
- APBB1 requireManualInspection "no".
- APBB1 summaryText "The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein , transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.".
- APBB1 updateCitations "yes".
- APBB1 updatePage "yes".
- APBB1 updateProteinBox "yes".
- APBB1 updateSummary "yes".
- APBB1 type Biomolecule.
- APBB1 type Protein.
- APBB1 type BiologicalObject.
- APBB1 comment "Amyloid beta A4 precursor protein-binding family B member 1 is a protein that in humans is encoded by the APBB1 gene.The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein.".
- APBB1 label "APBB1".
- APBB1 label "APBB1".
- APBB1 sameAs APBB1.
- APBB1 sameAs m.03gwpjr.
- APBB1 sameAs Q795054.
- APBB1 sameAs Q795054.
- APBB1 wasDerivedFrom APBB1?oldid=603295006.
- APBB1 isPrimaryTopicOf APBB1.