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- ATOH1 abstract "Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene.This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells (goblet, enteroendocrine, and Paneth cells). ATOH1 is a mammalian homolog of the Drosophila melanogaster gene atonal. ATOH1 is considered part of the Notch signaling pathway.In 2009, ATOH1 was identified as a "cancer switch-off" gene. [3]".
- ATOH1 entrezgene "474".
- ATOH1 wikiPageExternalLink ALeqM5hQ2QmN4PXatalHzUnF-7BM1f78rA.
- ATOH1 wikiPageExternalLink 22179.
- ATOH1 wikiPageID "14877709".
- ATOH1 wikiPageRevisionID "605949864".
- ATOH1 activates HES6.
- ATOH1 hasPhotoCollection ATOH1.
- ATOH1 requireManualInspection "no".
- ATOH1 summaryText "This protein belongs to the basic helix-loop-helix family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells . ATOH1 is a mammalian homolog of the Drosophila melanogaster gene atonal. ATOH1 is considered part of the Notch signaling pathway. In 2009, ATOH1 was identified as a "cancer switch-off" gene. http://www.google.com/hostednews/ukpress/article/ALeqM5hQ2QmN4PXatalHzUnF-7BM1f78rA".
- ATOH1 updateCitations "yes".
- ATOH1 updatePage "yes".
- ATOH1 updateProteinBox "yes".
- ATOH1 updateSummary "no".
- ATOH1 subject Category:Transcription_factors.
- ATOH1 type Biomolecule.
- ATOH1 type Protein.
- ATOH1 type BiologicalObject.
- ATOH1 comment "Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene.This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types.".
- ATOH1 label "ATOH1".
- ATOH1 sameAs m.03g__3m.
- ATOH1 sameAs Q4654777.
- ATOH1 sameAs Q4654777.
- ATOH1 wasDerivedFrom ATOH1?oldid=605949864.
- ATOH1 isPrimaryTopicOf ATOH1.