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- ATP6V0C abstract "V-type proton ATPase 16 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0C gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.".
- ATP6V0C entrezgene "527".
- ATP6V0C wikiPageID "14777317".
- ATP6V0C wikiPageRevisionID "590714349".
- ATP6V0C hasPhotoCollection ATP6V0C.
- ATP6V0C requireManualInspection "no".
- ATP6V0C summaryText "This gene encodes a component of vacuolar ATPase , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.".
- ATP6V0C updateCitations "yes".
- ATP6V0C updatePage "yes".
- ATP6V0C updateProteinBox "yes".
- ATP6V0C updateSummary "yes".
- ATP6V0C type Biomolecule.
- ATP6V0C type Protein.
- ATP6V0C type BiologicalObject.
- ATP6V0C comment "V-type proton ATPase 16 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0C gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.".
- ATP6V0C label "ATP6V0C".
- ATP6V0C sameAs m.03gxpfb.
- ATP6V0C sameAs Q4654839.
- ATP6V0C sameAs Q4654839.
- ATP6V0C wasDerivedFrom ATP6V0C?oldid=590714349.
- ATP6V0C isPrimaryTopicOf ATP6V0C.