Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ATP6V0E1> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- ATP6V0E1 abstract "V-type proton ATPase subunit e 1 is an enzyme that in humans is encoded by the ATP6V0E1 gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dogs, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3.".
- ATP6V0E1 entrezgene "8992".
- ATP6V0E1 wikiPageID "14876084".
- ATP6V0E1 wikiPageRevisionID "603595341".
- ATP6V0E1 hasPhotoCollection ATP6V0E1.
- ATP6V0E1 requireManualInspection "no".
- ATP6V0E1 summaryText "This gene encodes a component of vacuolar ATPase , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dogs, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3.".
- ATP6V0E1 updateCitations "yes".
- ATP6V0E1 updatePage "yes".
- ATP6V0E1 updateProteinBox "yes".
- ATP6V0E1 updateSummary "yes".
- ATP6V0E1 type Biomolecule.
- ATP6V0E1 type Protein.
- ATP6V0E1 type BiologicalObject.
- ATP6V0E1 comment "V-type proton ATPase subunit e 1 is an enzyme that in humans is encoded by the ATP6V0E1 gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.".
- ATP6V0E1 label "ATP6V0E1".
- ATP6V0E1 sameAs m.03g_wyc.
- ATP6V0E1 sameAs Q4654842.
- ATP6V0E1 sameAs Q4654842.
- ATP6V0E1 wasDerivedFrom ATP6V0E1?oldid=603595341.
- ATP6V0E1 isPrimaryTopicOf ATP6V0E1.