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- Abscopal_effect abstract "The abscopal effect is a phenomenon in the treatment of metastatic cancer where localized irradiation of a tumor causes not only a shrinking of the irradiated tumor but also a shrinking of tumors far from the irradiated area. While this phenomenon is extremely rare, its effect on the cancer can be stunning, leading to the disappearance of malignant growths throughout the entire body. Such success has been described for a variety of cancers, including melanoma, lymphoma, and kidney cancer.Scientists are not certain how the abscopal effect works to eliminate cancer in patients. Studies in mice suggest that the effect may depend upon activation of the immune system. In a case study reported at Memorial Sloan-Kettering Cancer Center in New York City, changes in a metastatic melanoma patient’s immune system were measured over the course of treatment. The team observed changes in tumor-directed antibody levels and immune cell populations that occurred at the time of the abscopal effect. These findings support the idea that radiation may help stimulate the immune system to fight cancer. At this time, T-cells and dendritic cells are believed to play a primary role.Effects in tissues adjacent to the irradiated area are bystander effects and are not necessarily mediated by the same mechanisms as abscopal effects.".
- Abscopal_effect wikiPageID "35026040".
- Abscopal_effect wikiPageRevisionID "600974434".
- Abscopal_effect hasPhotoCollection Abscopal_effect.
- Abscopal_effect subject Category:Cancer_treatments.
- Abscopal_effect subject Category:Medical_treatments.
- Abscopal_effect type Abstraction100002137.
- Abscopal_effect type Act100030358.
- Abscopal_effect type Activity100407535.
- Abscopal_effect type CancerTreatments.
- Abscopal_effect type Care100654885.
- Abscopal_effect type Event100029378.
- Abscopal_effect type MedicalTreatments.
- Abscopal_effect type PsychologicalFeature100023100.
- Abscopal_effect type Treatment100658082.
- Abscopal_effect type Work100575741.
- Abscopal_effect type YagoPermanentlyLocatedEntity.
- Abscopal_effect comment "The abscopal effect is a phenomenon in the treatment of metastatic cancer where localized irradiation of a tumor causes not only a shrinking of the irradiated tumor but also a shrinking of tumors far from the irradiated area. While this phenomenon is extremely rare, its effect on the cancer can be stunning, leading to the disappearance of malignant growths throughout the entire body.".
- Abscopal_effect label "Abscopal effect".
- Abscopal_effect label "Effet abscopal".
- Abscopal_effect sameAs Effet_abscopal.
- Abscopal_effect sameAs m.0j62kft.
- Abscopal_effect sameAs Q4669679.
- Abscopal_effect sameAs Q4669679.
- Abscopal_effect sameAs Abscopal_effect.
- Abscopal_effect wasDerivedFrom Abscopal_effect?oldid=600974434.
- Abscopal_effect isPrimaryTopicOf Abscopal_effect.