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- Abzyme abstract "An abzyme (from antibody and enzyme), also called catmab (from catalytic monoclonal antibody), is a monoclonal antibody with catalytic activity. Molecules which are modified to gain new catalytic activity are called synzymes. Abzymes are usually artificial constructs, but are also found in normal humans (anti-vasoactive intestinal peptide autoantibodies) and in patients with autoimmune diseases such as systemic lupus erythematosus, where they can bind to and hydrolyze DNA. Abzymes are potential tools in biotechnology, e.g., to perform specific actions on DNA. They are also useful in hydrolysis of esters. Rate of hydrolysis was increased 100 times.Enzymes function by lowering the activation energy of the transition state, thereby catalyzing the formation of an otherwise less-favorable molecular intermediate between reactants and products. If an antibody is developed to stabilize a molecule that's similar to an unstable intermediate of another (potentially unrelated) reaction, the developed antibody will enzymatically bind to and stabilize the intermediate state, thus catalyzing the reaction. A new and unique type of enzyme is produced.".
- Abzyme wikiPageID "1908".
- Abzyme wikiPageRevisionID "604160016".
- Abzyme hasPhotoCollection Abzyme.
- Abzyme subject Category:Monoclonal_antibodies.
- Abzyme type Abstraction100002137.
- Abzyme type Antibody115027189.
- Abzyme type Chemical114806838.
- Abzyme type Compound114818238.
- Abzyme type Macromolecule114944888.
- Abzyme type Material114580897.
- Abzyme type Matter100020827.
- Abzyme type Molecule114682133.
- Abzyme type MonoclonalAntibodies.
- Abzyme type MonoclonalAntibody115029781.
- Abzyme type OrganicCompound114727670.
- Abzyme type Part113809207.
- Abzyme type PhysicalEntity100001930.
- Abzyme type Protein114728724.
- Abzyme type Relation100031921.
- Abzyme type Substance100019613.
- Abzyme type Thing100002452.
- Abzyme type Unit109465459.
- Abzyme comment "An abzyme (from antibody and enzyme), also called catmab (from catalytic monoclonal antibody), is a monoclonal antibody with catalytic activity. Molecules which are modified to gain new catalytic activity are called synzymes. Abzymes are usually artificial constructs, but are also found in normal humans (anti-vasoactive intestinal peptide autoantibodies) and in patients with autoimmune diseases such as systemic lupus erythematosus, where they can bind to and hydrolyze DNA.".
- Abzyme label "Abzima".
- Abzyme label "Abzima".
- Abzyme label "Abzyme".
- Abzyme label "Abzyme".
- Abzyme label "Abzymy".
- Abzyme label "Anticorps catalytique".
- Abzyme label "Абзимы".
- Abzyme label "抗体酵素".
- Abzyme label "抗体酶".
- Abzyme sameAs Abzyme.
- Abzyme sameAs Abzima.
- Abzyme sameAs Anticorps_catalytique.
- Abzyme sameAs Abzima.
- Abzyme sameAs 抗体酵素.
- Abzyme sameAs Abzymy.
- Abzyme sameAs m.0v2s.
- Abzyme sameAs Q336782.
- Abzyme sameAs Q336782.
- Abzyme sameAs Abzyme.
- Abzyme wasDerivedFrom Abzyme?oldid=604160016.
- Abzyme isPrimaryTopicOf Abzyme.