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- Adenomatous_polyposis_coli abstract "Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer.APC is classified as a tumor suppressor gene. Tumor suppressor genes prevent the uncontrolled growth of cells that may result in cancerous tumors. The protein made by the APC gene plays a critical role in several cellular processes that determine whether a cell may develop into a tumor. The APC protein helps control how often a cell divides, how it attaches to other cells within a tissue, or whether a cell moves within or away from a tissue. This protein also helps ensure that the chromosome number in cells produced through cell division is correct. The APC protein accomplishes these tasks mainly through association with other proteins, especially those that are involved in cell attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation of beta-catenin prevents genes that stimulate cell division from being turned on too often and prevents cell overgrowth.The human APC gene is located on the long (q) arm of chromosome 5 in band q22.2 The APC gene has been shown to contain an internal ribosome entry site. APC orthologs have also been identified in all mammals for which complete genome data are available.".
- Adenomatous_polyposis_coli entrezgene "324".
- Adenomatous_polyposis_coli wikiPageExternalLink index.cfm.
- Adenomatous_polyposis_coli wikiPageExternalLink carddisp?APC.
- Adenomatous_polyposis_coli wikiPageExternalLink NBK1345.
- Adenomatous_polyposis_coli wikiPageExternalLink 175100,276300,611731,175100,276300,611731.
- Adenomatous_polyposis_coli wikiPageID "3568172".
- Adenomatous_polyposis_coli wikiPageRevisionID "604561900".
- Adenomatous_polyposis_coli hasPhotoCollection Adenomatous_polyposis_coli.
- Adenomatous_polyposis_coli subject Category:Human_genes.
- Adenomatous_polyposis_coli subject Category:Human_proteins.
- Adenomatous_polyposis_coli subject Category:Tumor_suppressor_genes.
- Adenomatous_polyposis_coli type Abstraction100002137.
- Adenomatous_polyposis_coli type Arrangement107938773.
- Adenomatous_polyposis_coli type Chemical114806838.
- Adenomatous_polyposis_coli type Compound114818238.
- Adenomatous_polyposis_coli type Gene105436752.
- Adenomatous_polyposis_coli type Genes.
- Adenomatous_polyposis_coli type Group100031264.
- Adenomatous_polyposis_coli type HumanProteins.
- Adenomatous_polyposis_coli type Macromolecule114944888.
- Adenomatous_polyposis_coli type Material114580897.
- Adenomatous_polyposis_coli type Matter100020827.
- Adenomatous_polyposis_coli type Molecule114682133.
- Adenomatous_polyposis_coli type Ordering108456993.
- Adenomatous_polyposis_coli type OrganicCompound114727670.
- Adenomatous_polyposis_coli type Part113809207.
- Adenomatous_polyposis_coli type PhysicalEntity100001930.
- Adenomatous_polyposis_coli type Protein114728724.
- Adenomatous_polyposis_coli type Relation100031921.
- Adenomatous_polyposis_coli type Sequence108459252.
- Adenomatous_polyposis_coli type Series108457976.
- Adenomatous_polyposis_coli type Substance100019613.
- Adenomatous_polyposis_coli type Suppressor105441468.
- Adenomatous_polyposis_coli type Thing100002452.
- Adenomatous_polyposis_coli type TumorSuppressorGene105441806.
- Adenomatous_polyposis_coli type TumorSuppressorGenes.
- Adenomatous_polyposis_coli type Unit109465459.
- Adenomatous_polyposis_coli type Biomolecule.
- Adenomatous_polyposis_coli type Protein.
- Adenomatous_polyposis_coli type BiologicalObject.
- Adenomatous_polyposis_coli comment "Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer.APC is classified as a tumor suppressor gene. Tumor suppressor genes prevent the uncontrolled growth of cells that may result in cancerous tumors. The protein made by the APC gene plays a critical role in several cellular processes that determine whether a cell may develop into a tumor.".
- Adenomatous_polyposis_coli label "APC (gen)".
- Adenomatous_polyposis_coli label "APC (gen)".
- Adenomatous_polyposis_coli label "Adenomatous Polyposis Coli".
- Adenomatous_polyposis_coli label "Adenomatous polyposis coli".
- Adenomatous_polyposis_coli label "Adenomatous-polyposis-coli-Protein".
- Adenomatous_polyposis_coli sameAs Adenomatous-polyposis-coli-Protein.
- Adenomatous_polyposis_coli sameAs APC_(gen).
- Adenomatous_polyposis_coli sameAs Adenomatous_Polyposis_Coli.
- Adenomatous_polyposis_coli sameAs APC_(gen).
- Adenomatous_polyposis_coli sameAs m.09m2ps.
- Adenomatous_polyposis_coli sameAs Q356062.
- Adenomatous_polyposis_coli sameAs Q356062.
- Adenomatous_polyposis_coli sameAs Adenomatous_polyposis_coli.
- Adenomatous_polyposis_coli wasDerivedFrom Adenomatous_polyposis_coli?oldid=604561900.
- Adenomatous_polyposis_coli isPrimaryTopicOf Adenomatous_polyposis_coli.