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- Adenylosuccinate_lyase abstract "Adenylosuccinate lyase (or adenylosuccinase) is an enzyme that in humans is encoded by the ADSL gene.Adenylosuccinate lyase converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. ASL catalyzes two reactions in the purine biosynthetic pathway that makes AMP; ASL cleaves adenylosuccinate into AMP and fumarate, and cleaves SAICAR into AICAR and fumarate.Adenylosuccinate lyase is part of the β-elimination superfamily of enzymes and it proceeds through an E1cb reaction mechanism. The enzyme is a homotetramer with three domains in each monomer and four active sites per homotetramer.Point mutations in adenylosuccinate that cause lowered enzymatic activity cause clinical symptoms that mark the condition adenylosuccinate lyase deficiency.This protein may use the morpheein model of allosteric regulation.".
- Adenylosuccinate_lyase entrezgene "158".
- Adenylosuccinate_lyase thumbnail ASL_active_sites.png?width=300.
- Adenylosuccinate_lyase wikiPageID "11289149".
- Adenylosuccinate_lyase wikiPageRevisionID "603829133".
- Adenylosuccinate_lyase caption "'The homotetrameric structure of ASL in Thermotoga maritima Domain 1 is in red, Domain 2 is in blue, Domain 3 is in yellow. This structure was inspired by an paper by Toth and Yeates".
- Adenylosuccinate_lyase casNumber "9027".
- Adenylosuccinate_lyase ecNumber "4.3".
- Adenylosuccinate_lyase goCode "70626".
- Adenylosuccinate_lyase hasPhotoCollection Adenylosuccinate_lyase.
- Adenylosuccinate_lyase iubmbEcNumber "4".
- Adenylosuccinate_lyase name "Adenylosuccinate lyase".
- Adenylosuccinate_lyase type Abstraction100002137.
- Adenylosuccinate_lyase type Activator114723079.
- Adenylosuccinate_lyase type Catalyst114723628.
- Adenylosuccinate_lyase type Chemical114806838.
- Adenylosuccinate_lyase type Compound114818238.
- Adenylosuccinate_lyase type Enzyme114732946.
- Adenylosuccinate_lyase type Macromolecule114944888.
- Adenylosuccinate_lyase type Material114580897.
- Adenylosuccinate_lyase type Matter100020827.
- Adenylosuccinate_lyase type Molecule114682133.
- Adenylosuccinate_lyase type OrganicCompound114727670.
- Adenylosuccinate_lyase type Part113809207.
- Adenylosuccinate_lyase type PhysicalEntity100001930.
- Adenylosuccinate_lyase type Protein114728724.
- Adenylosuccinate_lyase type Relation100031921.
- Adenylosuccinate_lyase type Substance100019613.
- Adenylosuccinate_lyase type Thing100002452.
- Adenylosuccinate_lyase type Unit109465459.
- Adenylosuccinate_lyase type Biomolecule.
- Adenylosuccinate_lyase type Protein.
- Adenylosuccinate_lyase type ProteinMolecule.
- Adenylosuccinate_lyase type BiologicalObject.
- Adenylosuccinate_lyase comment "Adenylosuccinate lyase (or adenylosuccinase) is an enzyme that in humans is encoded by the ADSL gene.Adenylosuccinate lyase converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle.".
- Adenylosuccinate_lyase label "Adenylosuccinat-Lyase".
- Adenylosuccinate_lyase label "Adenylosuccinate lyase".
- Adenylosuccinate_lyase label "Adénylosuccinate lyase".
- Adenylosuccinate_lyase sameAs Adenylosuccinat-Lyase.
- Adenylosuccinate_lyase sameAs Adénylosuccinate_lyase.
- Adenylosuccinate_lyase sameAs m.02r6g6y.
- Adenylosuccinate_lyase sameAs Q356244.
- Adenylosuccinate_lyase sameAs Q356244.
- Adenylosuccinate_lyase sameAs Adenylosuccinate_lyase.
- Adenylosuccinate_lyase wasDerivedFrom Adenylosuccinate_lyase?oldid=603829133.
- Adenylosuccinate_lyase depiction ASL_active_sites.png.
- Adenylosuccinate_lyase isPrimaryTopicOf Adenylosuccinate_lyase.