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- Adipiplon abstract "Adipiplon (NG2-73) is an anxiolytic drug developed by Neurogen Corporation. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. Adipiplon is a subtype-selective GABAA receptor partial agonist, which binds preferentially to the α3 subtype. This is significant as while several previous nonbenzodiazepine drugs have been developed that are selective for α2/3 over the other subtypes, adipiplon is one of the first drugs selected for clinical development which is able to discriminate between α2 and α3, as well as showing little affinity for the α1 or α5 subtypes - alpidem is selective for α3 over α2, but still has moderate affinity for α1, whereas adipiplon is highly α3-selective with little affinity for either α1, α2 or α5. Adipiplon is being researched as a potential medication for the treatment of anxiety and insomnia, and is currently (as of 2008) in Phase IIb trials.".
- Adipiplon atcPrefix "none".
- Adipiplon casNumber "840486-93-3".
- Adipiplon fdaUniiCode "OPL214POJ1".
- Adipiplon iupacName "7-[(2-(3-fluoropyridin-2-yl)-1H-imidazol-1-yl)methyl]-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine".
- Adipiplon thumbnail Adipiplon.svg?width=300.
- Adipiplon wikiPageID "16738700".
- Adipiplon wikiPageRevisionID "448084104".
- Adipiplon atcPrefix "none".
- Adipiplon c "18".
- Adipiplon casNumber "840486".
- Adipiplon chemspiderid "9373993".
- Adipiplon f "1".
- Adipiplon h "18".
- Adipiplon hasPhotoCollection Adipiplon.
- Adipiplon inchi "1".
- Adipiplon inchikey "UAMAIHOEGLEXSV-UHFFFAOYAD".
- Adipiplon iupacName "7".
- Adipiplon kegg "D08840".
- Adipiplon legalStatus "Uncontrolled".
- Adipiplon molecularWeight "351.38".
- Adipiplon n "7".
- Adipiplon routesOfAdministration "Oral".
- Adipiplon smiles "n4cnc1n4cncCn2ccnc2-c3ncccc3F".
- Adipiplon stdinchi "1".
- Adipiplon stdinchikey "UAMAIHOEGLEXSV-UHFFFAOYSA-N".
- Adipiplon unii "OPL214POJ1".
- Adipiplon verifiedrevid "444860495".
- Adipiplon subject Category:Anxiolytics.
- Adipiplon subject Category:Imidazoles.
- Adipiplon subject Category:Organofluorides.
- Adipiplon subject Category:Pyridines.
- Adipiplon subject Category:Triazolopyrimidines.
- Adipiplon type Abstraction100002137.
- Adipiplon type Base114618253.
- Adipiplon type Chemical114806838.
- Adipiplon type Compound114818238.
- Adipiplon type Imidazole114916670.
- Adipiplon type Imidazoles.
- Adipiplon type Material114580897.
- Adipiplon type Matter100020827.
- Adipiplon type Part113809207.
- Adipiplon type PhysicalEntity100001930.
- Adipiplon type Pyridine114692510.
- Adipiplon type Pyridines.
- Adipiplon type Relation100031921.
- Adipiplon type Substance100019613.
- Adipiplon type Drug.
- Adipiplon type DrugProduct.
- Adipiplon type FunctionalSubstance.
- Adipiplon comment "Adipiplon (NG2-73) is an anxiolytic drug developed by Neurogen Corporation. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. Adipiplon is a subtype-selective GABAA receptor partial agonist, which binds preferentially to the α3 subtype.".
- Adipiplon label "Adipiplon".
- Adipiplon sameAs m.0404mf8.
- Adipiplon sameAs Q4682933.
- Adipiplon sameAs Q4682933.
- Adipiplon sameAs Adipiplon.
- Adipiplon wasDerivedFrom Adipiplon?oldid=448084104.
- Adipiplon depiction Adipiplon.svg.
- Adipiplon isPrimaryTopicOf Adipiplon.