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- Albiglutide abstract "Albiglutide is a glucagon-like peptide-1 agonist (GLP-1 agonist) drug under investigation by GlaxoSmithKline for treatment of type 2 diabetes.It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of four to seven days, which is considerably longer than the other two GLP-1 analogs approved for market use, exenatide (Byetta) and liraglutide (Victoza). GLP-1 drugs are currently only available for subcutaneous administration on a daily basis, so a GLP-1 drug with a longer half-life is desirable. Such a drug would only need to be injected biweekly or weekly instead of daily, reducing the discomfort and inconvenience of GLP-1 administration considerably.It has not yet been determined whether albiglutide is as effective an antidiabetic agent as GLP-1 drugs currently on the market, and final data remains to be published regarding the incidence of adverse effects related to the drug. To evaluate the efficacy and safety of the drug, albiglutide is undergoing eight Phase III clinical trials. Four of these trials should report useful data by end 2010.6GSK filed for FDA approval on 01/14/2013 and European Medical Agency (EMA) on 03/07/2013. On 08/02/2013 GSK released a press release pushing the marketing date 3 months to 04/15/2014. In March 2014, GlaxoSmithKline PLC received approval from the European Commission to market albiglutide under the name 'Eperzan'. In April 2014, the FDA approved albiglutide under the name Tanzeum.".
- Albiglutide atcPrefix "None".
- Albiglutide casNumber "782500-75-8".
- Albiglutide wikiPageExternalLink regulatory-update--albiglutide-us-pdufa-date-extended-by-three-m.html.
- Albiglutide wikiPageID "20735586".
- Albiglutide wikiPageRevisionID "604341888".
- Albiglutide atcPrefix "None".
- Albiglutide c "3232".
- Albiglutide casNumber "782500".
- Albiglutide drugName "Albiglutide".
- Albiglutide eliminationHalfLife "-604800.0".
- Albiglutide h "5032".
- Albiglutide hasPhotoCollection Albiglutide.
- Albiglutide legalStatus "Investigational".
- Albiglutide molecularWeight "72970".
- Albiglutide n "864".
- Albiglutide o "979".
- Albiglutide s "41".
- Albiglutide subject Category:Anti-diabetic_drugs.
- Albiglutide type Agent114778436.
- Albiglutide type Anti-diabeticDrugs.
- Albiglutide type CausalAgent100007347.
- Albiglutide type Drug103247620.
- Albiglutide type Matter100020827.
- Albiglutide type PhysicalEntity100001930.
- Albiglutide type Substance100020090.
- Albiglutide type Drug.
- Albiglutide type FunctionalSubstance.
- Albiglutide comment "Albiglutide is a glucagon-like peptide-1 agonist (GLP-1 agonist) drug under investigation by GlaxoSmithKline for treatment of type 2 diabetes.It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of four to seven days, which is considerably longer than the other two GLP-1 analogs approved for market use, exenatide (Byetta) and liraglutide (Victoza).".
- Albiglutide label "Albiglutide".
- Albiglutide sameAs m.056wfj1.
- Albiglutide sameAs Q4712362.
- Albiglutide sameAs Q4712362.
- Albiglutide sameAs Albiglutide.
- Albiglutide wasDerivedFrom Albiglutide?oldid=604341888.
- Albiglutide isPrimaryTopicOf Albiglutide.
- Albiglutide name "Albiglutide".