Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Alcuronium_chloride> ?p ?o. }
Showing items 1 to 66 of
66
with 100 items per page.
- Alcuronium_chloride abstract "Alcuronium is a neuromuscular blocking (NMB) agent, alternatively referred to as a skeletal muscle relaxant. It is a semi-synthetic substance prepared from C-toxiferine I, a bis-quaternary alkaloid obtained from Strychnos toxifera. C-toxiferine I itself has been tested for its pharmacological action and noted to be a very long acting neuromuscular blocking agent For a formal definition of the durations of actions associated with NMB agents, see page for gantacurium. The replacement of both the N-methyl groups with N-allyl moieties yielded N,N-diallyl-bis-nortoxiferine, now recognized as alcuornium (and at one time marketed as the proprietary agent called Alloferin).Inclusion of the allylic functions presented an enhanced potential area of biotransformation, and thus alcuronium is observed to have a much shorter duration of neuromuscular blocking action than its parent C-toxiferine I. It also has a more rapid onset of action, and is ~1.5 times as potent as tubocurarine. The pharmacological action of alcuronium is readily reversed by neostigmine, and it produced little histamine release. The major disadvantage of alcuronium is that it elicits a vagolytic effect produced by a selective atropoine-like blockade of cardiac muscarinic receptors.".
- Alcuronium_chloride atcPrefix "M03".
- Alcuronium_chloride atcSuffix "AA01".
- Alcuronium_chloride casNumber "23214-96-2".
- Alcuronium_chloride chEBI "31185".
- Alcuronium_chloride fdaUniiCode "490DW6501Y".
- Alcuronium_chloride iupacName "4,4'-Didemethyl-4,4'-di-propenyltoxiferin-1-dichloride".
- Alcuronium_chloride pubchem "5311001".
- Alcuronium_chloride thumbnail Alcuroniumchlorid.svg?width=300.
- Alcuronium_chloride wikiPageID "6139936".
- Alcuronium_chloride wikiPageRevisionID "541750480".
- Alcuronium_chloride atcPrefix "M03".
- Alcuronium_chloride atcSuffix "AA01".
- Alcuronium_chloride c "44".
- Alcuronium_chloride casNumber "23214".
- Alcuronium_chloride charge "+2".
- Alcuronium_chloride chebi "31185".
- Alcuronium_chloride chemspiderid "20118193".
- Alcuronium_chloride excretion "14400.0".
- Alcuronium_chloride h "50".
- Alcuronium_chloride hasPhotoCollection Alcuronium_chloride.
- Alcuronium_chloride image "Alcuronium3d.png".
- Alcuronium_chloride inchi "1".
- Alcuronium_chloride inchikey "CPYGBGOXCJJJGC-CITJCSJLBO".
- Alcuronium_chloride iupacName "44".
- Alcuronium_chloride iupharLigand "341".
- Alcuronium_chloride metabolism "not metabolized".
- Alcuronium_chloride molecularWeight "666.894".
- Alcuronium_chloride n "4".
- Alcuronium_chloride o "2".
- Alcuronium_chloride pubchem "5311001".
- Alcuronium_chloride smiles "[Cl-].[Cl-].OC\C=C6\C[N@+]4CC[C@@]58c%11ccccc%11N7\C=C9\[C@H]1C[C@H]2[C@@]%10c3ccccc3N[C@@H]9%10".
- Alcuronium_chloride stdinchi "1".
- Alcuronium_chloride stdinchikey "CPYGBGOXCJJJGC-GKLGUMFISA-L".
- Alcuronium_chloride unii "490".
- Alcuronium_chloride verifiedfields "changed".
- Alcuronium_chloride verifiedrevid "477314883".
- Alcuronium_chloride subject Category:Muscle_relaxants.
- Alcuronium_chloride subject Category:World_Health_Organization_essential_medicines.
- Alcuronium_chloride type Abstraction100002137.
- Alcuronium_chloride type Cognition100023271.
- Alcuronium_chloride type Content105809192.
- Alcuronium_chloride type Discipline105996646.
- Alcuronium_chloride type KnowledgeDomain105999266.
- Alcuronium_chloride type LifeScience106037298.
- Alcuronium_chloride type MedicalScience106045562.
- Alcuronium_chloride type Medicine106043075.
- Alcuronium_chloride type NaturalScience106000400.
- Alcuronium_chloride type PsychologicalFeature100023100.
- Alcuronium_chloride type Science105999797.
- Alcuronium_chloride type WorldHealthOrganizationEssentialMedicines.
- Alcuronium_chloride type Drug.
- Alcuronium_chloride type FunctionalSubstance.
- Alcuronium_chloride comment "Alcuronium is a neuromuscular blocking (NMB) agent, alternatively referred to as a skeletal muscle relaxant. It is a semi-synthetic substance prepared from C-toxiferine I, a bis-quaternary alkaloid obtained from Strychnos toxifera. C-toxiferine I itself has been tested for its pharmacological action and noted to be a very long acting neuromuscular blocking agent For a formal definition of the durations of actions associated with NMB agents, see page for gantacurium.".
- Alcuronium_chloride label "Alcuronium chloride".
- Alcuronium_chloride label "Alcuronium".
- Alcuronium_chloride label "Alcuroniumchlorid".
- Alcuronium_chloride sameAs Alcuroniumchlorid.
- Alcuronium_chloride sameAs Alcuronium.
- Alcuronium_chloride sameAs m.0fs6zy.
- Alcuronium_chloride sameAs Q411049.
- Alcuronium_chloride sameAs Q411049.
- Alcuronium_chloride sameAs Alcuronium_chloride.
- Alcuronium_chloride wasDerivedFrom Alcuronium_chloride?oldid=541750480.
- Alcuronium_chloride depiction Alcuroniumchlorid.svg.
- Alcuronium_chloride isPrimaryTopicOf Alcuronium_chloride.