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- Alprazolam abstract "Alprazolam /ælˈpræzəlæm/ (trade name Xanax /zˈænæks/), available under other generic names, is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA gamma-amino-butyric acid receptor. Alprazolam is commonly used and FDA approved for the medical treatment of panic disorder, and anxiety disorders, such as generalized anxiety disorder (GAD) or social anxiety disorder (SAD). Alprazolam is available for oral administration in compressed tablet (CT) and extended-release capsule (XR) formulations. Alprazolam possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, and amnestic properties.Alprazolam has a fast onset of action and symptomatic relief. Ninety percent of peak effects are achieved within the first hour of using either in preparation for panic disorder, and full peak effects are achieved in 1.5 and 1.6 hours respectively. Peak benefits achieved for generalized anxiety disorder (GAD) may take up to a week.Tolerance to the anxiolytic/antipanic effects is controversial with some authoritative sources reporting the development of tolerance, and others reporting no development of tolerance; tolerance will however, develop to the sedative-hypnotic effects within a couple of days. Withdrawal symptoms or rebound symptoms may occur after ceasing treatment abruptly following a few weeks or longer of steady dosing, and may necessitate a gradual dose reduction.Alprazolam is the most prescribed and the most misused benzodiazepine on the U.S. retail market. The potential for misuse among those taking it for medical reasons is controversial with some expert reviews stating that the risk is low and similar to that of other benzodiazepine drugs and others stating that there is a substantial risk of abuse and dependence in both patients and non-medical users of alprazolam and that the pharmacological properties of alprazolam, high affinity binding, high potency, having a short elimination half-life as well as a rapid onset of action increase the misuse potential of alprazolam. Compared to the large number of prescriptions, relatively few individuals increase their dose on their own initiative or engage in drug-seeking behavior. Alprazolam is classified as a schedule IV controlled substance by the U.S. Drug Enforcement Administration (DEA).".
- Alprazolam atcPrefix "N05".
- Alprazolam atcSuffix "BA12".
- Alprazolam bioavailability "80.0".
- Alprazolam casNumber "28981-97-7".
- Alprazolam chEBI "2611".
- Alprazolam drugbank "DB00404".
- Alprazolam fdaUniiCode "YU55MQ3IZY".
- Alprazolam iupacName "8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine".
- Alprazolam pubchem "2118".
- Alprazolam thumbnail Alprazolam.svg?width=300.
- Alprazolam wikiPageExternalLink dpdirect.jsp?name=Alprazolam.
- Alprazolam wikiPageExternalLink alprazolam.shtml.
- Alprazolam wikiPageID "243513".
- Alprazolam wikiPageRevisionID "606688902".
- Alprazolam atcPrefix "N05".
- Alprazolam atcSuffix "BA12".
- Alprazolam bioavailability "80".
- Alprazolam c "17".
- Alprazolam casNumber "28981".
- Alprazolam chebi "2611".
- Alprazolam chembl "661".
- Alprazolam chemspiderid "2034".
- Alprazolam cl "1".
- Alprazolam dependencyLiability "High".
- Alprazolam drugbank "DB00404".
- Alprazolam eliminationHalfLife "40320.0".
- Alprazolam eliminationHalfLife "56880.0".
- Alprazolam excretion Kidney.
- Alprazolam h "13".
- Alprazolam hasPhotoCollection Alprazolam.
- Alprazolam image "Alprazolam3Dan.gif".
- Alprazolam inchi "1".
- Alprazolam iupacName "8".
- Alprazolam kegg "D00225".
- Alprazolam legalAu "S8".
- Alprazolam legalUk "POM".
- Alprazolam legalUs "Schedule IV".
- Alprazolam medlineplus "a684001".
- Alprazolam metabolism "Hepatic, via Cytochrome P450 3A4".
- Alprazolam molecularWeight "308.765".
- Alprazolam n "4".
- Alprazolam pregnancyUs "D".
- Alprazolam pubchem "2118".
- Alprazolam routesOfAdministration "Oral, Sublingual".
- Alprazolam smiles "ClC1=CC2=CN3C=NN=C3CN=C2C4=CC=CC=C4".
- Alprazolam stdinchi "1".
- Alprazolam stdinchikey "VREFGVBLTWBCJP-UHFFFAOYSA-N".
- Alprazolam tradename "Xanax".
- Alprazolam unii "YU55MQ3IZY".
- Alprazolam verifiedrevid "477164519".
- Alprazolam watchedfields "changed".
- Alprazolam width "200".
- Alprazolam width "250".
- Alprazolam subject Category:Benzodiazepines.
- Alprazolam subject Category:Organochlorides.
- Alprazolam subject Category:Pfizer.
- Alprazolam subject Category:Triazolobenzodiazepines.
- Alprazolam type Drug.
- Alprazolam type DrugProduct.
- Alprazolam type FunctionalSubstance.
- Alprazolam comment "Alprazolam /ælˈpræzəlæm/ (trade name Xanax /zˈænæks/), available under other generic names, is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA gamma-amino-butyric acid receptor. Alprazolam is commonly used and FDA approved for the medical treatment of panic disorder, and anxiety disorders, such as generalized anxiety disorder (GAD) or social anxiety disorder (SAD).".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Alprazolam".
- Alprazolam label "Алпразолам".
- Alprazolam label "ألبرازولام".
- Alprazolam label "アルプラゾラム".
- Alprazolam label "阿普唑仑".
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs アルプラゾラム.
- Alprazolam sameAs 알프라졸람.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs Alprazolam.
- Alprazolam sameAs m.01k9cw.
- Alprazolam sameAs Q319877.
- Alprazolam sameAs Q319877.
- Alprazolam sameAs ALPRAZOLAM.
- Alprazolam sameAs DB00404.
- Alprazolam sameAs 2118.
- Alprazolam wasDerivedFrom Alprazolam?oldid=606688902.
- Alprazolam depiction Alprazolam.svg.
- Alprazolam isPrimaryTopicOf Alprazolam.