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- Amiflamine abstract "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons. In other words, at low doses, it can be used to selectively inhibit MAO-A enzymes in serotonin cells, whereas at higher doses it loses its selectivity. This property is attributed to amiflamine's higher affinity for the serotonin transporter over the norepinephrine and dopamine transporters, as transporter-mediated carriage is required for amiflamine to enter monoaminergic neurons.".
- Amiflamine atcPrefix "none".
- Amiflamine casNumber "77518-07-1".
- Amiflamine fdaUniiCode "NE25WV9C8S".
- Amiflamine iupacName "4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline".
- Amiflamine pubchem "71221".
- Amiflamine thumbnail Amiflamine.svg?width=300.
- Amiflamine wikiPageID "26338492".
- Amiflamine wikiPageRevisionID "606733427".
- Amiflamine atcPrefix "none".
- Amiflamine c "12".
- Amiflamine casNumber "77518".
- Amiflamine chembl "30344".
- Amiflamine chemspiderid "64356".
- Amiflamine h "20".
- Amiflamine hasPhotoCollection Amiflamine.
- Amiflamine inchi "1".
- Amiflamine inchikey "HFQMYSHATTXRTC-JTQLQIEIBH".
- Amiflamine iupacName "4".
- Amiflamine legalStatus "Uncontrolled".
- Amiflamine molecularWeight "192.3".
- Amiflamine n "2".
- Amiflamine pubchem "71221".
- Amiflamine routesOfAdministration "Oral".
- Amiflamine smiles "NC".
- Amiflamine stdinchi "1".
- Amiflamine stdinchikey "HFQMYSHATTXRTC-JTQLQIEISA-N".
- Amiflamine synonyms "-4".
- Amiflamine unii "NE25WV9C8S".
- Amiflamine verifiedfields "changed".
- Amiflamine verifiedrevid "454124445".
- Amiflamine width "175".
- Amiflamine subject Category:Anilines.
- Amiflamine subject Category:Phenethylamines.
- Amiflamine type Abstraction100002137.
- Amiflamine type AliphaticCompound114601294.
- Amiflamine type Amine114739004.
- Amiflamine type Aniline114754505.
- Amiflamine type Anilines.
- Amiflamine type Chemical114806838.
- Amiflamine type Compound114818238.
- Amiflamine type Material114580897.
- Amiflamine type Matter100020827.
- Amiflamine type MethaneSeries114951377.
- Amiflamine type OrganicCompound114727670.
- Amiflamine type Part113809207.
- Amiflamine type PhysicalEntity100001930.
- Amiflamine type Relation100031921.
- Amiflamine type Substance100019613.
- Amiflamine type Drug.
- Amiflamine type DrugProduct.
- Amiflamine type FunctionalSubstance.
- Amiflamine comment "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons.".
- Amiflamine label "Amiflamine".
- Amiflamine sameAs m.0bbyrd8.
- Amiflamine sameAs Q4746184.
- Amiflamine sameAs Q4746184.
- Amiflamine sameAs Amiflamine.
- Amiflamine wasDerivedFrom Amiflamine?oldid=606733427.
- Amiflamine depiction Amiflamine.svg.
- Amiflamine isPrimaryTopicOf Amiflamine.