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- Amorolfine abstract "Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes. Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine as the active ingredient. It is used to treat onychomycosis (fungal infection of the toe- and fingernails). Amorolfine 5% nail lacquer in once-weekly or twice-weekly applications has been shown in two studies to be between 60% and 71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment) were 38% and 46%. However, full experimental details of these trials were not available and since they were first reported in 1992 there have been no subsequent trials.It is a topical solution for the treatment of toenail infections. Systemic treatments may be considered more effective.It is approved for sale over the counter in Australia and the UK (recently re-classified to over the counter status), and is approved for the treatment of toenail fungus by prescription in other countries. It is not approved for the treatment of onychomycosis in the United States or Canada, but can be ordered from there by mail from other countries.".
- Amorolfine atcPrefix "D01".
- Amorolfine atcSuffix "AE16".
- Amorolfine casNumber "78613-35-1".
- Amorolfine chEBI "599440".
- Amorolfine fdaUniiCode "AB0BHP2FH0".
- Amorolfine iupacName "(±)-(2R*,6S*)-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine".
- Amorolfine pubchem "54260".
- Amorolfine thumbnail Amorolfine.svg?width=300.
- Amorolfine wikiPageID "11569843".
- Amorolfine wikiPageRevisionID "594806779".
- Amorolfine atcPrefix "D01".
- Amorolfine atcSuffix "AE16".
- Amorolfine c "21".
- Amorolfine casNumber "78613".
- Amorolfine chebi "599440".
- Amorolfine chembl "489411".
- Amorolfine chemspiderid "49010".
- Amorolfine h "35".
- Amorolfine hasPhotoCollection Amorolfine.
- Amorolfine inchi "1".
- Amorolfine inchikey "MQHLMHIZUIDKOO-AYHJJNSGBZ".
- Amorolfine iupacName "--2,6-dimethyl-4-{2-methyl-3-[4-phenyl]propyl}morpholine".
- Amorolfine kegg "D02923".
- Amorolfine molecularWeight "317.509".
- Amorolfine n "1".
- Amorolfine o "1".
- Amorolfine pubchem "54260".
- Amorolfine smiles "O2[C@@H]C".
- Amorolfine stdinchi "1".
- Amorolfine stdinchikey "MQHLMHIZUIDKOO-AYHJJNSGSA-N".
- Amorolfine unii "AB0BHP2FH0".
- Amorolfine verifiedrevid "443386467".
- Amorolfine watchedfields "changed".
- Amorolfine subject Category:Antifungals.
- Amorolfine subject Category:Morpholines.
- Amorolfine type Agent114778436.
- Amorolfine type Antifungal102720201.
- Amorolfine type Antifungals.
- Amorolfine type CausalAgent100007347.
- Amorolfine type Matter100020827.
- Amorolfine type PhysicalEntity100001930.
- Amorolfine type Substance100020090.
- Amorolfine type Drug.
- Amorolfine type DrugProduct.
- Amorolfine type FunctionalSubstance.
- Amorolfine comment "Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes. Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine as the active ingredient. It is used to treat onychomycosis (fungal infection of the toe- and fingernails).".
- Amorolfine label "Amorolfin".
- Amorolfine label "Amorolfina".
- Amorolfine label "Amorolfina".
- Amorolfine label "Amorolfina".
- Amorolfine label "Amorolfina".
- Amorolfine label "Amorolfine".
- Amorolfine label "Amorolfine".
- Amorolfine sameAs Amorolfin.
- Amorolfine sameAs Amorolfina.
- Amorolfine sameAs Amorolfine.
- Amorolfine sameAs Amorolfina.
- Amorolfine sameAs Amorolfina.
- Amorolfine sameAs Amorolfina.
- Amorolfine sameAs m.02rjj99.
- Amorolfine sameAs Q123195.
- Amorolfine sameAs Q123195.
- Amorolfine sameAs Amorolfine.
- Amorolfine wasDerivedFrom Amorolfine?oldid=594806779.
- Amorolfine depiction Amorolfine.svg.
- Amorolfine isPrimaryTopicOf Amorolfine.