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- Apomorphine abstract "Apomorphine (Apokyn, Ixense, Spontane, Uprima) is a non-selective dopamine agonist which activates both D1-like and D2-like receptors, with some preference for the latter subtypes. It is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix. Apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors. The apo- prefix relates to it being an aporphine derivative.Historically, apomorphine has been tried for a variety of uses including psychiatric treatment of homosexuality in the early 20th century, and more recently in treating erectile dysfunction. Currently, apomorphine is used in the treatment of Parkinson's disease. It is a potent emetic (i.e., it induces vomiting) and should not be administered without an antiemetic such as domperidone. The emetic properties of apomorphine are exploited in veterinary medicine to induce therapeutic emesis in canines that have recently ingested toxic or foreign substances.It was also successfully used as an unofficial treatment of heroin addiction, a purpose for which it was championed by the author William S. Burroughs. A recent study indicates that apomorphine might be a suitable marker for assessing central dopamine system alterations associated with chronic heroin consumption. There is, however, no clinical evidence that apomorphine is an effective and safe treatment regimen for opiate addiction. Early studies involved aversion therapy in alcoholism and anxiety, and modern reports are rather anecdotal.".
- Apomorphine atcPrefix "G04".
- Apomorphine atcSuffix "BE07".
- Apomorphine bioavailability "100.0".
- Apomorphine casNumber "58-00-4".
- Apomorphine chEBI "48538".
- Apomorphine drugbank "DB00714".
- Apomorphine fdaUniiCode "F39049Y068".
- Apomorphine iupacName "(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol".
- Apomorphine pubchem "6005".
- Apomorphine thumbnail Apomorphine.png?width=300.
- Apomorphine wikiPageExternalLink pdsp.php.
- Apomorphine wikiPageExternalLink 280.pdf.
- Apomorphine wikiPageExternalLink www.apo-go.co.uk.
- Apomorphine wikiPageID "2985223".
- Apomorphine wikiPageRevisionID "604495335".
- Apomorphine atcPrefix "G04".
- Apomorphine atcSuffix "BE07".
- Apomorphine bioavailability "100".
- Apomorphine c "17".
- Apomorphine casNumber "58".
- Apomorphine chebi "48538".
- Apomorphine chembl "53".
- Apomorphine chemspiderid "5783".
- Apomorphine drugbank "DB00714".
- Apomorphine eliminationHalfLife "2400.0".
- Apomorphine h "17".
- Apomorphine hasPhotoCollection Apomorphine.
- Apomorphine image "Apomorphine_3d.gif".
- Apomorphine inchi "1".
- Apomorphine inchikey "VMWNQDUVQKEIOC-CYBMUJFWBH".
- Apomorphine iupacName "-6".
- Apomorphine iupharLigand "33".
- Apomorphine kegg "D07460".
- Apomorphine legalStatus "Rx-only".
- Apomorphine medlineplus "a604020".
- Apomorphine metabolism Liver.
- Apomorphine molecularWeight "267.322".
- Apomorphine n "1".
- Apomorphine o "2".
- Apomorphine pregnancyCategory "C".
- Apomorphine proteinBound "~50%".
- Apomorphine pubchem "6005".
- Apomorphine routesOfAdministration Oral_administration.
- Apomorphine routesOfAdministration Subcutaneous_tissue.
- Apomorphine smiles "OC1=CC=C4C=C1".
- Apomorphine stdinchi "1".
- Apomorphine stdinchikey "VMWNQDUVQKEIOC-CYBMUJFWSA-N".
- Apomorphine tradename "Apokyn".
- Apomorphine unii "F39049Y068".
- Apomorphine verifiedfields "changed".
- Apomorphine verifiedrevid "457135730".
- Apomorphine watchedfields "changed".
- Apomorphine subject Category:Catechols.
- Apomorphine subject Category:Dibenzoquinolines.
- Apomorphine subject Category:Dopamine_agonists.
- Apomorphine subject Category:Erectile_dysfunction_drugs.
- Apomorphine subject Category:Sexual_orientation_and_medicine.
- Apomorphine type Drug.
- Apomorphine type DrugProduct.
- Apomorphine type FunctionalSubstance.
- Apomorphine comment "Apomorphine (Apokyn, Ixense, Spontane, Uprima) is a non-selective dopamine agonist which activates both D1-like and D2-like receptors, with some preference for the latter subtypes. It is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix. Apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors.".
- Apomorphine label "Apomorfina".
- Apomorphine label "Apomorfina".
- Apomorphine label "Apomorfina".
- Apomorphine label "Apomorfina".
- Apomorphine label "Apomorphin".
- Apomorphine label "Apomorphine".
- Apomorphine label "Apomorphine".
- Apomorphine label "Апоморфин".
- Apomorphine label "アポモルヒネ".
- Apomorphine sameAs Apomorfin.
- Apomorphine sameAs Apomorphin.
- Apomorphine sameAs Apomorfina.
- Apomorphine sameAs Apomorphine.
- Apomorphine sameAs Apomorfina.
- Apomorphine sameAs アポモルヒネ.
- Apomorphine sameAs Apomorfina.
- Apomorphine sameAs Apomorfina.
- Apomorphine sameAs m.08hsmg.
- Apomorphine sameAs Q269111.
- Apomorphine sameAs Q269111.
- Apomorphine sameAs apomorphine.
- Apomorphine sameAs DB00714.
- Apomorphine sameAs 2215.
- Apomorphine wasDerivedFrom Apomorphine?oldid=604495335.
- Apomorphine depiction Apomorphine.png.
- Apomorphine isPrimaryTopicOf Apomorphine.