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- Aprepitant abstract "Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. It was approved by the FDA in 2003.Aprepitant may also be useful in the treatment of cyclic vomiting syndrome & late-stage chemotherapy induced vomiting, but there are few studies to date.On January 2008, the FDA approved fosaprepitant, an intravenous form of aprepitant, which is to be sold under the tradename Emend Injection in the US and as Ivemend in some other countries.".
- Aprepitant atcPrefix "A04".
- Aprepitant atcSuffix "AD12".
- Aprepitant bioavailability "60.0".
- Aprepitant casNumber "170729-80-3".
- Aprepitant chEBI "499361".
- Aprepitant drugbank "DB00673".
- Aprepitant fdaUniiCode "1NF15YR6UY".
- Aprepitant iupacName "5-([(2R,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluorophenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one".
- Aprepitant pubchem "6918365".
- Aprepitant thumbnail Aprepitant2DACS.svg?width=300.
- Aprepitant wikiPageExternalLink www.emend.com.
- Aprepitant wikiPageExternalLink aprepitant.
- Aprepitant wikiPageExternalLink emend_pi.pdf.
- Aprepitant wikiPageID "1505732".
- Aprepitant wikiPageRevisionID "596046001".
- Aprepitant atcPrefix "A04".
- Aprepitant atcSuffix "AD12".
- Aprepitant bioavailability "60".
- Aprepitant c "23".
- Aprepitant casNumber "170729".
- Aprepitant chebi "499361".
- Aprepitant chembl "1471".
- Aprepitant chemspiderid "5293568".
- Aprepitant drugbank "DB00673".
- Aprepitant eliminationHalfLife "-46800.0".
- Aprepitant excretion "Urine , faeces".
- Aprepitant f "7".
- Aprepitant h "21".
- Aprepitant hasPhotoCollection Aprepitant.
- Aprepitant image "Aprepitant3Dan.gif".
- Aprepitant inchi "1".
- Aprepitant inchikey "ATALOFNDEOCMKK-OITMNORJBX".
- Aprepitant iupacName "5".
- Aprepitant legalAu "S4".
- Aprepitant legalUk "POM".
- Aprepitant legalUs "Rx-only".
- Aprepitant medlineplus "a604003".
- Aprepitant metabolism "Hepatic".
- Aprepitant molecularWeight "534.427".
- Aprepitant n "4".
- Aprepitant o "3".
- Aprepitant pregnancyAu "B1".
- Aprepitant pregnancyUs "B".
- Aprepitant proteinBound ">95%".
- Aprepitant pubchem "6918365".
- Aprepitant routesOfAdministration "Oral".
- Aprepitant smiles "FCc1cc[C@H]C".
- Aprepitant stdinchi "1".
- Aprepitant stdinchikey "ATALOFNDEOCMKK-OITMNORJSA-N".
- Aprepitant tradename "Emend".
- Aprepitant unii "1".
- Aprepitant verifiedrevid "457136600".
- Aprepitant width "200".
- Aprepitant width "250".
- Aprepitant subject Category:Antiemetics.
- Aprepitant subject Category:Lactams.
- Aprepitant subject Category:Morpholines.
- Aprepitant subject Category:NK1_receptor_antagonists.
- Aprepitant subject Category:Organofluorides.
- Aprepitant subject Category:Triazoles.
- Aprepitant subject Category:Ureas.
- Aprepitant type Adversary109773245.
- Aprepitant type CausalAgent100007347.
- Aprepitant type LivingThing100004258.
- Aprepitant type NK1ReceptorAntagonists.
- Aprepitant type Object100002684.
- Aprepitant type Organism100004475.
- Aprepitant type Person100007846.
- Aprepitant type PhysicalEntity100001930.
- Aprepitant type Whole100003553.
- Aprepitant type YagoLegalActor.
- Aprepitant type YagoLegalActorGeo.
- Aprepitant type Drug.
- Aprepitant type DrugProduct.
- Aprepitant type FunctionalSubstance.
- Aprepitant comment "Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.".
- Aprepitant label "Aprepitant".
- Aprepitant label "Aprepitant".
- Aprepitant label "Aprepitant".
- Aprepitant label "Aprepitant".
- Aprepitant label "Aprepitanto".
- Aprepitant label "Aprépitant".
- Aprepitant sameAs Aprepitant.
- Aprepitant sameAs Aprepitant.
- Aprepitant sameAs Aprépitant.
- Aprepitant sameAs Aprepitant.
- Aprepitant sameAs Aprepitanto.
- Aprepitant sameAs m.056ll1.
- Aprepitant sameAs Q621834.
- Aprepitant sameAs Q621834.
- Aprepitant sameAs aprepitant.
- Aprepitant sameAs DB00673.
- Aprepitant sameAs 151165.
- Aprepitant sameAs Aprepitant.
- Aprepitant wasDerivedFrom Aprepitant?oldid=596046001.
- Aprepitant depiction Aprepitant2DACS.svg.
- Aprepitant isPrimaryTopicOf Aprepitant.