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- Arbaclofen_placarbil abstract "Arbaclofen placarbil (ar-BAC-loe-fen pla-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.".
- Arbaclofen_placarbil atcPrefix "none".
- Arbaclofen_placarbil casNumber "847353-30-4".
- Arbaclofen_placarbil iupacName "(3R)-3-(4-chlorophenyl)-4-[(1S)-2-methyl-1-[(2-methylpropanoyl)oxy]propoxy]carbonyl]amino]butanoic acid".
- Arbaclofen_placarbil pubchem "11281011".
- Arbaclofen_placarbil thumbnail Arbaclofen_placarbil.svg?width=300.
- Arbaclofen_placarbil wikiPageID "39566174".
- Arbaclofen_placarbil wikiPageRevisionID "601790750".
- Arbaclofen_placarbil atcPrefix "none".
- Arbaclofen_placarbil c "19".
- Arbaclofen_placarbil casNumber "847353".
- Arbaclofen_placarbil chemspiderid "9456008".
- Arbaclofen_placarbil cl "1".
- Arbaclofen_placarbil h "26".
- Arbaclofen_placarbil inchi "1".
- Arbaclofen_placarbil inchikey "JXTAALBWJQJLGN-KSSFIOAIBU".
- Arbaclofen_placarbil iupacName "-3".
- Arbaclofen_placarbil kegg "D08861".
- Arbaclofen_placarbil legalStatus "Development terminated".
- Arbaclofen_placarbil molecularWeight "399.86".
- Arbaclofen_placarbil n "1".
- Arbaclofen_placarbil o "6".
- Arbaclofen_placarbil pregnancyCategory "N/A".
- Arbaclofen_placarbil pubchem "11281011".
- Arbaclofen_placarbil smiles "CC[C@@H]OCNC[C@H]C1=CC=CCl".
- Arbaclofen_placarbil stdinchi "1".
- Arbaclofen_placarbil stdinchikey "JXTAALBWJQJLGN-KSSFIOAISA-N".
- Arbaclofen_placarbil width "260".
- Arbaclofen_placarbil subject Category:Amino_acids.
- Arbaclofen_placarbil subject Category:GABA_agonists.
- Arbaclofen_placarbil subject Category:Organochlorides.
- Arbaclofen_placarbil subject Category:Prodrugs.
- Arbaclofen_placarbil type Drug.
- Arbaclofen_placarbil type FunctionalSubstance.
- Arbaclofen_placarbil comment "Arbaclofen placarbil (ar-BAC-loe-fen pla-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.".
- Arbaclofen_placarbil label "Arbaclofen placarbil".
- Arbaclofen_placarbil sameAs m.0vxgmz4.
- Arbaclofen_placarbil sameAs Q15408425.
- Arbaclofen_placarbil sameAs Q15408425.
- Arbaclofen_placarbil wasDerivedFrom Arbaclofen_placarbil?oldid=601790750.
- Arbaclofen_placarbil depiction Arbaclofen_placarbil.svg.
- Arbaclofen_placarbil isPrimaryTopicOf Arbaclofen_placarbil.