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- Arrestin_beta_2 abstract "Beta-arrestin-2, also known as arrestin beta-2, is an intracellular protein that in humans is encoded by the ARRB2 gene.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.The protein may interact with the agonist DOI in 5-HT2A receptor signaling.".
- Arrestin_beta_2 entrezgene "409".
- Arrestin_beta_2 wikiPageID "14415818".
- Arrestin_beta_2 wikiPageRevisionID "590653457".
- Arrestin_beta_2 hasPhotoCollection Arrestin_beta_2.
- Arrestin_beta_2 requireManualInspection "no".
- Arrestin_beta_2 updateCitations "yes".
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- Arrestin_beta_2 updateProteinBox "yes".
- Arrestin_beta_2 updateSummary "no".
- Arrestin_beta_2 type Biomolecule.
- Arrestin_beta_2 type Protein.
- Arrestin_beta_2 type ProteinMolecule.
- Arrestin_beta_2 type BiologicalObject.
- Arrestin_beta_2 comment "Beta-arrestin-2, also known as arrestin beta-2, is an intracellular protein that in humans is encoded by the ARRB2 gene.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right.".
- Arrestin_beta_2 label "Arrestin beta 2".
- Arrestin_beta_2 label "Arrestina beta 2".
- Arrestin_beta_2 sameAs Arrestina_beta_2.
- Arrestin_beta_2 sameAs m.03d2v0k.
- Arrestin_beta_2 sameAs Q4795934.
- Arrestin_beta_2 sameAs Q4795934.
- Arrestin_beta_2 wasDerivedFrom Arrestin_beta_2?oldid=590653457.
- Arrestin_beta_2 isPrimaryTopicOf Arrestin_beta_2.