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- Ars_operon abstract "In molecular biology, the ars operon is an operon found in several bacterial taxon. It is required for the detoxification of arsenate, arsenite, and antimonite. This system transports arsenite and antimonite out of the cell. The pump is composed of two polypeptides, the products of the arsA and arsB genes. This two-subunit enzyme produces resistance to arsenite and antimonite. Arsenate, however, must first be reduced to arsenite before it is extruded. A third gene, arsC, expands the substrate specificity to allow for arsenate pumping and resistance. ArsC is an approximately 150-residue arsenate reductase that uses reduced glutathione (GSH) to convert arsenate to arsenite with a redox active cysteine residue in the active site. ArsC forms an active quaternary complex with GSH, arsenate, and glutaredoxin 1 (Grx1). The three ligands must be present simultaneously for reduction to occur.".
- Ars_operon symbol "ArsA_ATPase".
- Ars_operon symbol "ArsB".
- Ars_operon symbol "ArsC".
- Ars_operon symbol "ArsD".
- Ars_operon thumbnail PDB_1rw1_EBI.jpg?width=300.
- Ars_operon wikiPageID "32148595".
- Ars_operon wikiPageRevisionID "590653615".
- Ars_operon caption "yffb protein".
- Ars_operon hasPhotoCollection Ars_operon.
- Ars_operon interpro "IPR000802".
- Ars_operon interpro "IPR006660".
- Ars_operon interpro "IPR010712".
- Ars_operon name "Anion-transporting ATPase".
- Ars_operon name "ArsB".
- Ars_operon name "ArsC".
- Ars_operon name "ArsD".
- Ars_operon pfam "PF02040".
- Ars_operon pfam "PF02374".
- Ars_operon pfam "PF03960".
- Ars_operon pfam "PF06953".
- Ars_operon pfamClan "CL0023".
- Ars_operon pfamClan "CL0172".
- Ars_operon pfamClan "CL0182".
- Ars_operon scop "1".
- Ars_operon scop "777600.0".
- Ars_operon symbol "ArsA_ATPase".
- Ars_operon symbol "ArsB".
- Ars_operon symbol "ArsC".
- Ars_operon symbol "ArsD".
- Ars_operon tcdb "3".
- Ars_operon subject Category:Protein_families.
- Ars_operon type Abstraction100002137.
- Ars_operon type Family108078020.
- Ars_operon type Group100031264.
- Ars_operon type Organization108008335.
- Ars_operon type ProteinFamilies.
- Ars_operon type SocialGroup107950920.
- Ars_operon type Unit108189659.
- Ars_operon type YagoLegalActor.
- Ars_operon type YagoLegalActorGeo.
- Ars_operon type YagoPermanentlyLocatedEntity.
- Ars_operon type Biomolecule.
- Ars_operon type Protein.
- Ars_operon type BiologicalObject.
- Ars_operon comment "In molecular biology, the ars operon is an operon found in several bacterial taxon. It is required for the detoxification of arsenate, arsenite, and antimonite. This system transports arsenite and antimonite out of the cell. The pump is composed of two polypeptides, the products of the arsA and arsB genes. This two-subunit enzyme produces resistance to arsenite and antimonite. Arsenate, however, must first be reduced to arsenite before it is extruded.".
- Ars_operon label "Ars operon".
- Ars_operon sameAs m.0gw_5xf.
- Ars_operon sameAs Q4796324.
- Ars_operon sameAs Q4796324.
- Ars_operon sameAs Ars_operon.
- Ars_operon wasDerivedFrom Ars_operon?oldid=590653615.
- Ars_operon depiction PDB_1rw1_EBI.jpg.
- Ars_operon isPrimaryTopicOf Ars_operon.