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- Arylsulfatase_B abstract "Arylsulfatase B (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase, EC 3.1.6.12) is an enzyme associated with mucopolysaccharidosis VI. Arylsulfatase B is among a group of arylsulfatase enzymes present in the lysosomes of the liver, pancreas, and kidneys of animals. The purpose of the enzyme is to hydrolyze sulfates in the body. ARSB does this by breaking down glycosaminoglycans(GAGs), which are large sugar molecules in the body. ARSB targets two GAGs in particular: dermatan sulfate and chondroitin sulfate.Over 130 mutations to ARSB have been found, each leading to a deficiency in the body. In most cases, the mutation occurs on a single nucleotide in the sequence. An arylsulfatase B deficiency can lead to an accumulation of GAGs in lysosomes, which in turn can lead to Maroteaux–Lamy syndrome, or mucopolysaccharidosis VI.".
- Arylsulfatase_B arm "p".
- Arylsulfatase_B band "11".
- Arylsulfatase_B chromosome "5".
- Arylsulfatase_B ecNumber "3.1.6.12".
- Arylsulfatase_B entrezgene "411".
- Arylsulfatase_B hgncid "714".
- Arylsulfatase_B locusSupplementaryData "-q13".
- Arylsulfatase_B omim "253200".
- Arylsulfatase_B refseq "NM_000046".
- Arylsulfatase_B symbol "ARSB".
- Arylsulfatase_B thumbnail Arylsulfatase_B.jpg?width=300.
- Arylsulfatase_B uniprot "P15848".
- Arylsulfatase_B wikiPageExternalLink ARSB.
- Arylsulfatase_B wikiPageExternalLink arylsulfatase.
- Arylsulfatase_B wikiPageExternalLink explore.do?structureId=3ED4.
- Arylsulfatase_B wikiPageExternalLink 3ED4_ram_m_500.pdf..
- Arylsulfatase_B wikiPageID "6701886".
- Arylsulfatase_B wikiPageRevisionID "589205723".
- Arylsulfatase_B arm "p".
- Arylsulfatase_B auto "yes".
- Arylsulfatase_B band "11".
- Arylsulfatase_B caption "Crystallographic structure of putative tetrameric arylsulfatase from Escherichia coli.".
- Arylsulfatase_B chromosome "5".
- Arylsulfatase_B date "December 2009".
- Arylsulfatase_B ecnumber "3.1".
- Arylsulfatase_B entrezgene "411".
- Arylsulfatase_B hasPhotoCollection Arylsulfatase_B.
- Arylsulfatase_B hgncid "714".
- Arylsulfatase_B locussupplementarydata "-q13".
- Arylsulfatase_B name "arylsulfatase B".
- Arylsulfatase_B omim "253200".
- Arylsulfatase_B refseq "NM_000046".
- Arylsulfatase_B symbol "ARSB".
- Arylsulfatase_B uniprot "P15848".
- Arylsulfatase_B type Biomolecule.
- Arylsulfatase_B type Protein.
- Arylsulfatase_B type ProteinMolecule.
- Arylsulfatase_B type BiologicalObject.
- Arylsulfatase_B comment "Arylsulfatase B (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase, EC 3.1.6.12) is an enzyme associated with mucopolysaccharidosis VI. Arylsulfatase B is among a group of arylsulfatase enzymes present in the lysosomes of the liver, pancreas, and kidneys of animals. The purpose of the enzyme is to hydrolyze sulfates in the body.".
- Arylsulfatase_B label "Arylsulfatase B".
- Arylsulfatase_B label "Arylsulfatase B".
- Arylsulfatase_B sameAs Arylsulfatase_B.
- Arylsulfatase_B sameAs m.0gj1s9.
- Arylsulfatase_B sameAs Q718087.
- Arylsulfatase_B sameAs Q718087.
- Arylsulfatase_B wasDerivedFrom Arylsulfatase_B?oldid=589205723.
- Arylsulfatase_B depiction Arylsulfatase_B.jpg.
- Arylsulfatase_B isPrimaryTopicOf Arylsulfatase_B.
- Arylsulfatase_B name "arylsulfatase B".