Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Azathioprine> ?p ?o. }
- Azathioprine abstract "Azathioprine (INN, /ˌæzəˈθaɪɵpriːn/, abbreviated AZA) is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years.Azathioprine acts as a prodrug for mercaptopurine, inhibiting an enzyme that is required for the synthesis of DNA. Thus it most strongly affects proliferating cells, such as the T cells and B cells of the immune system.The main adverse effect of azathioprine is bone marrow suppression, which can be life-threatening, especially in people with a genetic deficiency of the enzyme thiopurine S-methyltransferase. It is also listed by the International Agency for Research on Cancer as a Group 1 carcinogen (carcinogenic to humans).Azathioprine is produced by a number of manufacturers under different brand names (Azasan by Salix in the U.S., Imuran by GlaxoSmithKline in Canada, the U.S., Australia, Ireland and the United Kingdom, Azamun in Finland and Imurel in Scandinavia and France, among others). It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.".
- Azathioprine atcPrefix "L04".
- Azathioprine atcSuffix "AX01".
- Azathioprine bioavailability "60.0".
- Azathioprine casNumber "446-86-6".
- Azathioprine casSupplemental "(sodium salt)".
- Azathioprine chEBI "2948".
- Azathioprine drugbank "DB00993".
- Azathioprine fdaUniiCode "MRK240IY2L".
- Azathioprine iupacName "6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine".
- Azathioprine pubchem "2265".
- Azathioprine thumbnail Azathioprine.svg?width=300.
- Azathioprine wikiPageExternalLink dpdirect.jsp?name=Azathioprine.
- Azathioprine wikiPageExternalLink Imuran.
- Azathioprine wikiPageExternalLink products_azasan.asp.
- Azathioprine wikiPageID "504543".
- Azathioprine wikiPageRevisionID "606812458".
- Azathioprine atcPrefix "L04".
- Azathioprine atcSuffix "AX01".
- Azathioprine bioavailability "60".
- Azathioprine c "9".
- Azathioprine casNumber "446".
- Azathioprine chebi "2948".
- Azathioprine chembl "1542".
- Azathioprine chemspiderid "2178".
- Azathioprine drugbank "DB00993".
- Azathioprine eliminationHalfLife "18000.0".
- Azathioprine eliminationHalfLife "4800.0".
- Azathioprine excretion "Renal, 98% as metabolites".
- Azathioprine h "7".
- Azathioprine hasPhotoCollection Azathioprine.
- Azathioprine image "Azathioprine3Dan.gif".
- Azathioprine inchi "1".
- Azathioprine inchikey "LMEKQMALGUDUQG-UHFFFAOYAK".
- Azathioprine iupacName "6".
- Azathioprine kegg "D00238".
- Azathioprine legalStatus "Rx-only".
- Azathioprine licenceUs "azathioprine".
- Azathioprine medlineplus "a682167".
- Azathioprine meltingHigh "245".
- Azathioprine meltingPoint "238".
- Azathioprine metabolism "Activated non-enzymatically, deactivated mainly by xanthine oxidase".
- Azathioprine molecularWeight "277.263".
- Azathioprine n "7".
- Azathioprine o "2".
- Azathioprine pregnancyAu "D".
- Azathioprine pregnancyUs "D".
- Azathioprine proteinBound "20".
- Azathioprine pubchem "2265".
- Azathioprine routesOfAdministration "Mainly oral".
- Azathioprine s "1".
- Azathioprine smiles "[O-][N+]c3ncnC".
- Azathioprine stdinchi "1".
- Azathioprine stdinchikey "LMEKQMALGUDUQG-UHFFFAOYSA-N".
- Azathioprine tradename "Azasan, Imuran and others".
- Azathioprine unii "MRK240IY2L".
- Azathioprine verifiedrevid "458437709".
- Azathioprine watchedfields "changed".
- Azathioprine width "150".
- Azathioprine width "200".
- Azathioprine subject Category:Antineoplastic_drugs.
- Azathioprine subject Category:Antirheumatic_products.
- Azathioprine subject Category:IARC_Group_1_carcinogens.
- Azathioprine subject Category:Immunosuppressants.
- Azathioprine subject Category:Nitroimidazoles.
- Azathioprine subject Category:Prodrugs.
- Azathioprine subject Category:Purine_antagonists.
- Azathioprine subject Category:Purines.
- Azathioprine subject Category:World_Health_Organization_essential_medicines.
- Azathioprine type Drug.
- Azathioprine type DrugProduct.
- Azathioprine type FunctionalSubstance.
- Azathioprine comment "Azathioprine (INN, /ˌæzəˈθaɪɵpriːn/, abbreviated AZA) is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years.Azathioprine acts as a prodrug for mercaptopurine, inhibiting an enzyme that is required for the synthesis of DNA.".
- Azathioprine label "Azathioprin".
- Azathioprine label "Azathioprine".
- Azathioprine label "Azathioprine".
- Azathioprine label "Azathioprine".
- Azathioprine label "Azatioprina".
- Azathioprine label "Azatioprina".
- Azathioprine label "Azatioprina".
- Azathioprine label "Azatiopryna".
- Azathioprine label "Азатиоприн".
- Azathioprine label "آزاثيوبرين".
- Azathioprine label "アザチオプリン".
- Azathioprine label "硫唑嘌呤".
- Azathioprine sameAs Azathioprin.
- Azathioprine sameAs Azatioprina.
- Azathioprine sameAs Azathioprine.
- Azathioprine sameAs Azatioprina.
- Azathioprine sameAs アザチオプリン.
- Azathioprine sameAs Azathioprine.
- Azathioprine sameAs Azatiopryna.
- Azathioprine sameAs Azatioprina.
- Azathioprine sameAs m.02jctp.
- Azathioprine sameAs Q18939.
- Azathioprine sameAs Q18939.
- Azathioprine sameAs azathioprine.
- Azathioprine sameAs DB00993.
- Azathioprine sameAs 2265.
- Azathioprine wasDerivedFrom Azathioprine?oldid=606812458.