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- BD1063 abstract "BD1063 or 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine.In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.".
- BD1063 casNumber "150208-28-9".
- BD1063 iupacName "1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine".
- BD1063 thumbnail BD1063.png?width=300.
- BD1063 wikiPageID "36174254".
- BD1063 wikiPageRevisionID "587300828".
- BD1063 c "13".
- BD1063 casNumber "150208".
- BD1063 cl "2".
- BD1063 h "18".
- BD1063 hasPhotoCollection BD1063.
- BD1063 iupacName "1".
- BD1063 molecularWeight "273.2".
- BD1063 n "2".
- BD1063 subject Category:Organochlorides.
- BD1063 subject Category:Piperazines.
- BD1063 type Drug.
- BD1063 type FunctionalSubstance.
- BD1063 comment "BD1063 or 1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine.In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.".
- BD1063 label "BD1063".
- BD1063 sameAs m.0ch4vps.
- BD1063 sameAs Q4835358.
- BD1063 sameAs Q4835358.
- BD1063 wasDerivedFrom BD1063?oldid=587300828.
- BD1063 depiction BD1063.png.
- BD1063 isPrimaryTopicOf BD1063.
